(2-Ethoxyethyl)triphenylphosphoniuM broMide

Base Information

• Chemical Name: (2-Ethoxyethyl)triphenylphosphoniuM broMide
• CAS No.: 25361-69-7
• Molecular Formula: C22H24 O P . Br
• Molecular Weight: 335.3986
• Mol file: 25361-69-7.mol

Synonyms:(2-Ethoxyethyl)triphenylphosphoniumbromide (7CI); Phosphonium, (2-ethoxyethyl)triphenyl-, bromide (8CI,9CI); NSC84061

Chemical Property of (2-Ethoxyethyl)triphenylphosphoniuM broMide

Chemical Property:

• Melting Point: 182 °C
• PSA: 22.82000
• LogP: 1.02100

Purity/Quality:

99% ^*data from raw suppliers

(2-Ethoxyethyl)triphenylphosphoniumbromide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2-Ethoxyethyl)triphenylphosphoniuM broMide

There total 5 articles about (2-Ethoxyethyl)triphenylphosphoniuM broMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

ethanol (64-17-5) + 2-(hydroxyethyl)triphenylphosphonium bromide (7237-34-5) → (2-ethoxyethyl)triphenylphosphonium bromide (25361-69-7)

Guidance literature:

With potassium hydroxide; at 80 ℃; for 24h;

Reference yield: 84.0%

2-Bromoethyl ethyl ether (592-55-2) + triphenylphosphine (603-35-0) → (2-ethoxyethyl)triphenylphosphonium bromide (25361-69-7)

Guidance literature:

In toluene; Heating;

DOI:10.1021/jm00396a008

Reference yield: 60.0%

ethanol (64-17-5) + dibromure de vinylene-1,2 bis-triphenylphosphonium → (E)-2-Ethoxyvinyl(triphenyl)phosphonium bromide (81149-97-5) + (2-ethoxyethyl)triphenylphosphonium bromide (25361-69-7)

Guidance literature:

With triethylamine; In dichloromethane; for 12h; Ambient temperature;

upstream raw materials:

sodium ethanolate

(2-phenoxyethyl)triphenylphosphonium bromide

ethanol

2-Bromoethyl ethyl ether

Downstream raw materials:

(S)-3-{4-[4-Benzenesulfonyloxy-3-((E)-3-ethoxy-propenyl)-phenoxy]-3,5-diiodo-phenyl}-2-(2,2,2-trifluoro-acetylamino)-propionic acid methyl ester

Refernces

• 1、 Cristau, Henri-Jean,Mouchet, Patrick. "ALKALINE HYDROLYSIS OF β AND γ-FUNCTIONAL PHOSPHONIUM SALTS". . p. 135 - 144. Retrieved 2007/10/03.
• 2、 Cristau, Henri-Jean,Bottaro, Denis,Plenat, Francoise,Pietrasanta, Francine,Christol, Henri. "SYNTHESE DE SELS DE VINYLPHOSPHONIUMS β-SUBSTITUES ET DE SELS D'ALKYLPHOSPHONIUMS β-DISUBSTITUES". . p. 63 - 72. Retrieved 2007/10/02.