4-(2-(p-Tolylamino)-4-thiazolyl)phenoxyacetic acid

Base Information

Chemical Name:4-(2-(p-Tolylamino)-4-thiazolyl)phenoxyacetic acid
CAS No.:168127-37-5
Molecular Formula:C₁₈H₁₆N₂O₃S
Molecular Weight:340.403
Hs Code.:
DSSTox Substance ID:DTXSID60168498
Wikidata:Q83038105
Mol file:168127-37-5.mol

Synonyms:168127-37-5;4-(2-(p-Tolylamino)-4-thiazolyl)phenoxyacetic acid;2-[4-[2-(4-methylanilino)-1,3-thiazol-4-yl]phenoxy]acetic acid;Acetic acid, (4-(2-((4-methylphenyl)amino)-4-thiazolyl)phenoxy)-;2-[4-[2-[(4-METHYLPHENYL)AMINO]-1,3-THIAZOL-4-YL]PHENOXY]ACETIC ACID;(4-(2-((4-Methylphenyl)amino)-4-thiazolyl)phenoxy)acetic acid;DTXSID60168498;[4-(2-p-Tolylamino-thiazol-4-yl)-phenoxy]-acetic acid

Suppliers and Price of 4-(2-(p-Tolylamino)-4-thiazolyl)phenoxyacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 4-(2-(p-Tolylamino)-4-thiazolyl)phenoxyacetic acid

Chemical Property:

Vapor Pressure:2.1E-13mmHg at 25°C
Boiling Point:560.6°Cat760mmHg
Flash Point:292.8°C
PSA：99.69000
Density:1.335g/cm³
LogP:4.39850
XLogP3:4.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:340.08816355
Heavy Atom Count:24
Complexity:407

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)NC2=NC(=CS2)C3=CC=C(C=C3)OCC(=O)O

Technology Process of 4-(2-(p-Tolylamino)-4-thiazolyl)phenoxyacetic acid

There total 5 articles about 4-(2-(p-Tolylamino)-4-thiazolyl)phenoxyacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 168127-32-0
ethyl 4-<2-(p-tolylamino)-4-thiazolyl>phenoxyacetate

: 168127-37-5
4-<2-(p-tolylamino)-4-thiazolyl>phenoxyacetic acid

Guidance literature:: With sulfuric acid; for 3h; Heating;

Reference yield:

: 51828-69-4
ethyl (4-acetylphenoxy)-acetate

: 168127-37-5
4-<2-(p-tolylamino)-4-thiazolyl>phenoxyacetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / acetonitrile / 3 h / Heating

2: 72 percent / ethanol / 6 h / Heating

3: 82 percent / 20percent H₂SO₄ / 3 h / Heating

With sulfuric acid; In ethanol; acetonitrile;

Reference yield:

: 754231-46-4
ethyl 4-(2-tosyloxyacetyl)phenoxyacetate

: 168127-37-5
4-<2-(p-tolylamino)-4-thiazolyl>phenoxyacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / ethanol / 6 h / Heating

2: 82 percent / 20percent H₂SO₄ / 3 h / Heating

With sulfuric acid; In ethanol;