Phyllanthin

Base Information

Chemical Name:Phyllanthin
CAS No.:10351-88-9
Molecular Formula:C24H34 O6
Molecular Weight:418.53
Hs Code.:2909309090
NSC Number:619043
UNII:75O1TFF47Z
DSSTox Substance ID:DTXSID001319088
Nikkaji Number:J1.896.977G
Wikidata:Q27107847
Metabolomics Workbench ID:68473
ChEMBL ID:CHEMBL1253999
Mol file:10351-88-9.mol

Synonyms:phyllanthin

Suppliers and Price of Phyllanthin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Phyllanthin
2.5mg
$ 185.00

Sigma-Aldrich
Phyllanthin analytical standard
10mg
$ 373.00

Sigma-Aldrich
Phyllanthin United States Pharmacopeia (USP) Reference Standard
15mg
$ 320.00

Medical Isotopes, Inc.
Phyllanthin
25 mg
$ 2400.00

Medical Isotopes, Inc.
Phyllanthin
2.5 mg
$ 675.00

Crysdot
Phyllanthin 95+%
5mg
$ 640.00

ChemScene
Phyllanthin 99.96%
5mg
$ 250.00

ChemScene
Phyllanthin 99.96%
1mg
$ 100.00

Cayman Chemical
Phyllanthin ≥98%
10mg
$ 300.00

Cayman Chemical
Phyllanthin ≥98%
1mg
$ 40.00

Total 50 raw suppliers

Chemical Property of Phyllanthin

Chemical Property:

Melting Point:96℃
Boiling Point:530.6°Cat760mmHg
Flash Point:207.3°C
PSA：55.38000
Density:1.069g/cm³
LogP:4.03140
XLogP3:4.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:13
Exact Mass:418.23553880
Heavy Atom Count:30
Complexity:407

Purity/Quality:

98%,99%, ^*data from raw suppliers

Phyllanthin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COCC(CC1=CC(=C(C=C1)OC)OC)C(CC2=CC(=C(C=C2)OC)OC)COC
Isomeric SMILES:COC[C@@H](CC1=CC(=C(C=C1)OC)OC)[C@H](CC2=CC(=C(C=C2)OC)OC)COC
Uses Phyllanthin is a chemical extract from the Phyllanthus niruri plant and displays pharmacological effects as an anti-diabetic action, anti-arthritic, and inhibitor of P-gp.

Technology Process of Phyllanthin

There total 11 articles about Phyllanthin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 138737-28-7
bromophyllanthin

: 10351-88-9,40516-27-6,123808-59-3
phyllanthin

Guidance literature:: In tetrahydrofuran; for 3h; ultrasound;
DOI:10.1016/S0040-4020(01)91020-8

Reference yield:

: 15813-34-0,15905-29-0,93609-04-2,126965-32-0
D_g-threo-2.3-bis-(3.4-dimethoxy-benzyl)-succinic acid

: 10351-88-9
(+)-phyllanthin

Guidance literature:: Multi-step reaction with 3 steps

2: LiAlH₄ / tetrahydrofuran

3: Ag₂O / dimethylformamide

With lithium aluminium tetrahydride; silver(l) oxide; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)82594-1

Reference yield:

: 15813-34-0,15905-29-0,93609-04-2,126965-32-0
D,L-2,3-bis(3,4-dimethoxybenzyl)succinic acid

: 10351-88-9
(+)-phyllanthin

Guidance literature:: Multi-step reaction with 4 steps

3: LiAlH₄ / tetrahydrofuran

4: Ag₂O / dimethylformamide

With lithium aluminium tetrahydride; silver(l) oxide; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)82594-1