3-Acetylbenzophenone

Base Information

Chemical Name:3-Acetylbenzophenone
CAS No.:66067-44-5
Molecular Formula:C15H12O2
Molecular Weight:224.259
Hs Code.:2914500000
UNII:3DQM4A09S7
DSSTox Substance ID:DTXSID80216268
Nikkaji Number:J2.996.132H
Wikidata:Q27257081

Synonyms:1-(3-Benzoylphenyl)ethanone;3-Acetylbenzophenone;3-Benzoylacetophenone;m-Benzoylacetophenone;

Suppliers and Price of 3-Acetylbenzophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Acetylbenzophenone
10mg
$ 160.00

TRC
3-Acetylbenzophenone
100mg
$ 1295.00

Sigma-Aldrich
Ketoprofen Related Compound D hydrochloride
20mg
$ 1160.00

Sigma-Aldrich
Ketoprofen impurity A European Pharmacopoeia (EP) Reference Standard
k2000010
$ 190.00

Crysdot
1-(3-Benzoylphenyl)ethanone 95+%
1g
$ 392.00

Biosynth Carbosynth
3-Acetylbenzophenone
5 mg
$ 300.00

Biosynth Carbosynth
3-Acetylbenzophenone
2 mg
$ 200.00

Biosynth Carbosynth
3-Acetylbenzophenone
1 mg
$ 125.00

Biosynth Carbosynth
3-Acetylbenzophenone
10 mg
$ 500.00

Biosynth Carbosynth
3-Acetylbenzophenone
25 mg
$ 700.00

Total 35 raw suppliers

Chemical Property of 3-Acetylbenzophenone

Chemical Property:

Vapor Pressure:3.73E-06mmHg at 25°C
Refractive Index:1.578
Boiling Point:385.7 °C at 760 mmHg
Flash Point:144.6 °C
PSA：34.14000
Density:1.126g/cm³
LogP:3.12020
Storage Temp.:2-8°C
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:224.083729621
Heavy Atom Count:17
Complexity:289

Purity/Quality:

99% ^*data from raw suppliers

3-Acetylbenzophenone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=CC(=CC=C1)C(=O)C2=CC=CC=C2
Uses 3-Acetylbenzophenone (Ketoprofen EP Impurity A) is a Ketoprofen intermediate. Ketoprofen USP Related Compound D.

Technology Process of 3-Acetylbenzophenone

There total 26 articles about 3-Acetylbenzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 135364-97-5
tert-butyl benzoyl(tert-butoxycarbonyl)carbamate

: 3-acetylphenylboronic acid

: 66067-44-5
(3-acetylphenyl)(phenyl)methanone

Guidance literature:: With (3-phenylallyl)(chloro)-[1,3-bis(2,6-diisopropylphenyl)-4,5-dihydroimidazol-2-ylidene]palladium(II); potassium carbonate; In tetrahydrofuran; water; at 23 ℃; for 15h; Inert atmosphere; Schlenk technique;
DOI:10.1021/acs.orglett.7b03191

Reference yield: 91.0%

: 93-99-2
benzoic acid phenyl ester

: 3-acetylphenylboronic acid

: 66067-44-5
(3-acetylphenyl)(phenyl)methanone

Guidance literature:: With potassium phosphate; (3-phenylallyl)(chloro)-[1,3-bis(2,6-diisopropylphenyl)-4,5-dihydroimidazol-2-ylidene]palladium(II); water; In tetrahydrofuran; at 90 ℃; for 2h; Inert atmosphere; Sealed tube; Schlenk technique;
DOI:10.1021/acs.6bl2329

Reference yield: 91.0%

: 6343-27-7
1-benzoylpyrrolidine-2,5-dione

: 3-acetylphenylboronic acid

: 66067-44-5
(3-acetylphenyl)(phenyl)methanone

Guidance literature:: With palladium diacetate; sodium carbonate; tricyclohexylphosphine tetrafluoroborate; In 1,4-dioxane; at 120 ℃; for 15h; Inert atmosphere; Schlenk technique;
DOI:10.1039/c7ob02269g