6-bromo-N-methylimidazo[1,2-a]pyrazin-8-amine

Base Information

• Chemical Name: 6-bromo-N-methylimidazo[1,2-a]pyrazin-8-amine
• CAS No.: 117718-85-1
• Molecular Formula: C₇H₇BrN₄
• Molecular Weight: 227.063
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID10151890
• Nikkaji Number: J510.333I
• Wikidata: Q83018436
• ChEMBL ID: CHEMBL114797
• Mol file: 117718-85-1.mol

Synonyms:6-bromo-N-methylimidazo[1,2-a]pyrazin-8-amine;117718-85-1;BRN 5810676;Imidazo(1,2-a)pyrazin-8-amine, 6-bromo-N-methyl-;CHEMBL114797;6-Bromo-N-methylimidazo(1,2-a)pyrazin-8-amine;pab13;PAB-13;SCHEMBL2273731;DTXSID10151890;BDBM50229881;AKOS016003001;AB09869;LS-80091

Chemical Property of 6-bromo-N-methylimidazo[1,2-a]pyrazin-8-amine

Chemical Property:

• Refractive Index: 1.737
• PSA: 42.22000
• Density: 1.81 g/cm³
• LogP: 1.60650
• XLogP3: 2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 225.98541
• Heavy Atom Count: 12
• Complexity: 166

Purity/Quality:

98%min ^*data from raw suppliers

6-Bromo-N-methylimidazo[1,2-a]pyrazin-8-amine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CNC1=NC(=CN2C1=NC=C2)Br

Technology Process of 6-bromo-N-methylimidazo[1,2-a]pyrazin-8-amine

There total 2 articles about 6-bromo-N-methylimidazo[1,2-a]pyrazin-8-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

→ 6-bromo-8-(methylamino)imidazo<1,2-α>pyrazine (117718-85-1)

Guidance literature:

Reference yield:

6,8-dibromoimidazo[1,2-a]pyrazine (63744-22-9) + methylamine (74-89-5) → 6-bromo-8-(methylamino)imidazo<1,2-α>pyrazine (117718-85-1)

Guidance literature:

In water; for 12h;

DOI:10.1021/jm00096a008

Reference yield:

6-bromo-8-(methylamino)imidazo<1,2-α>pyrazine (117718-85-1) → imidazo[1,2-a]pyrazin-8-yl-methyl-amine (117718-89-5)

Guidance literature:

With hydrogen; palladium on activated charcoal;

DOI:10.1021/jm00096a008

upstream raw materials:

6,8-dibromoimidazo[1,2-a]pyrazine

methylamine

Downstream raw materials:

imidazo[1,2-a]pyrazin-8-yl-methyl-amine