4-bromophenyl 4-chlorobenzoate

Base Information

• Chemical Name: 4-bromophenyl 4-chlorobenzoate
• CAS No.: 37038-56-5
• Molecular Formula: C13H8 Br Cl O2
• Molecular Weight: 311.562
• Mol file: 37038-56-5.mol

Synonyms:Benzoicacid, p-chloro-, p-bromophenyl ester (8CI); 4-Bromophenyl 4-chlorobenzoate; NSC76784; p-Bromophenyl p-chlorobenzoate

Chemical Property of 4-bromophenyl 4-chlorobenzoate

Chemical Property:

• Vapor Pressure: 1.41E-06mmHg at 25°C
• Boiling Point: 399°Cat760mmHg
• Flash Point: 195.1°C
• Density: 1.55g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-bromophenyl 4-chlorobenzoate

There total 6 articles about 4-bromophenyl 4-chlorobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

1-Chloro-4-iodobenzene (637-87-6) + 4-bromo-phenol (106-41-2) + carbon monoxide (201230-82-2) → p-bromophenyl ester of p-chlorobenzoic acid (37038-56-5)

Guidance literature:

With sodium hydroxide; palladium diacetate; In N,N-dimethyl-formamide; at 60 ℃; for 8h; under 760 Torr;

Reference yield: 70.0%

4-bromo-phenol (106-41-2) + para-chlorobenzoic acid (74-11-3) → p-bromophenyl ester of p-chlorobenzoic acid (37038-56-5)

Guidance literature:

With tetrachloromethane; triethylamine; triphenylphosphine; In acetonitrile; for 4h; Ambient temperature;

DOI:10.1246/bcsj.54.2227

Reference yield: 54.0%

4-bromo-phenol (106-41-2) + para-chlorobenzoic acid (74-11-3) → phenyl 4-chlorobenzoate (1871-38-1) + p-bromophenyl ester of p-chlorobenzoic acid (37038-56-5)

Guidance literature:

With triethylamine; triphenylphosphine; at 170 ℃; for 4h;

DOI:10.1246/bcsj.54.2839

upstream raw materials:

1-Chloro-4-iodobenzene

4-bromo-phenol

carbon monoxide

para-chlorobenzoic acid

Downstream raw materials:

4-phenylphenyl 4-chlorobenzoate

(5-Bromo-2-hydroxy-phenyl)-(4-chloro-phenyl)-methanone