DIETHYL ASPARTATE

Base Information

• Chemical Name: DIETHYL ASPARTATE
• CAS No.: 13552-87-9
• Molecular Formula: C8H15 N O4
• Molecular Weight: 189.211
• Hs Code.: 2922499990
• Mol file: 13552-87-9.mol

Synonyms:Asparticacid, diethyl ester, L- (6CI,7CI,8CI); L-Aspartic acid, diethyl ester (9CI);(S)-Aspartic acid diethyl ester; Aspartic acid diethyl ester; DiethylL-aspartate; Diethyl aspartate; L-Aspartic diethyl ester;O,O-Diethyl-L-aspartic acid

Chemical Property of DIETHYL ASPARTATE

Chemical Property:

• Vapor Pressure: 0.0129mmHg at 25°C
• Melting Point: 178-180 °C
• Boiling Point: 259.5°Cat760mmHg
• PKA: 6.19±0.33(Predicted)
• Flash Point: 97.5°C
• PSA: 78.62000
• Density: 1.102g/cm³
• LogP: 0.53030

Purity/Quality:

99% ^*data from raw suppliers

(S)-diethyl2-aminosuccinate 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DIETHYL ASPARTATE

There total 7 articles about DIETHYL ASPARTATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

diethyl L-aspartate hydrochloride (16115-68-7) → L-aspartic acid diethyl ester (13552-87-9)

Guidance literature:

With Amberlyst A₂₁ resin; In dichloromethane; at 0 - 20 ℃; for 2h;

DOI:10.1002/chem.202101439

Reference yield: 88.0%

diethyl N-benzyloxycarbonyl-(S)-aspartate (57471-70-2) → L-aspartic acid diethyl ester (13552-87-9)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In ethanol; at 20 ℃; for 2h; under 760.051 Torr;

DOI:10.1016/j.bmcl.2021.128267

Reference yield:

ethanol (64-17-5) + L-Aspartic acid (56-84-8,25608-40-6,27881-03-4,32505-46-7,52526-39-3) → L-aspartic acid diethyl ester (13552-87-9)

Guidance literature:

With hydrogenchloride;

upstream raw materials:

ethanol

L-asparagine

L-Aspartic acid

DL-aspartic acid diethyl ester

Downstream raw materials:

N-phenylsulfanylcarbonyl-L-aspartic acid diethyl ester

γ-Glu-asp

diethyl N²,N⁶-bis((benzyloxy)carbonyl)-L-lysyl-L-aspartate

L-Aspartic acid