2,4-Diamino-5-(3,5-dimethoxy-4-(methoxymethyl)benzyl)pyrimidine

Base Information

Chemical Name:2,4-Diamino-5-(3,5-dimethoxy-4-(methoxymethyl)benzyl)pyrimidine
CAS No.:55687-86-0
Molecular Formula:C15H20N4O3
Molecular Weight:304.3443
Hs Code.:
DSSTox Substance ID:DTXSID70877862
Nikkaji Number:J1.575.128B
Wikidata:Q82859755

Synonyms:5-(3,5-Dimethoxy-4-(methoxymethyl)benzyl)pyrimidine-2,4-diamine;55687-86-0;BRN 0697193;2,4-Diamino-5-(3,5-dimethoxy-4-(methoxymethyl)benzyl)pyrimidine;2,4-Pyrimidinediamine, 5-((3,5-dimethoxy-4-(methoxymethyl)phenyl)methyl)-;5-((3,5-Dimethoxy-4-(methoxymethyl)phenyl)methyl)-2,4-pyrimidinediamine;SCHEMBL11849472;DTXSID70877862;24NH2PYRIMIDIN,5(35-MEO-4-MEO-CH2)BENZYL

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Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2,4-Diamino-5-(3,5-dimethoxy-4-(methoxymethyl)benzyl)pyrimidine

Chemical Property:

Vapor Pressure:3.85E-11mmHg at 25°C
Boiling Point:525.6°Cat760mmHg
Flash Point:271.7°C
PSA：105.51000
Density:1.232g/cm³
LogP:2.55780
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:304.15354051
Heavy Atom Count:22
Complexity:320

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COCC1=C(C=C(C=C1OC)CC2=CN=C(N=C2N)N)OC

Technology Process of 2,4-Diamino-5-(3,5-dimethoxy-4-(methoxymethyl)benzyl)pyrimidine

There total 8 articles about 2,4-Diamino-5-(3,5-dimethoxy-4-(methoxymethyl)benzyl)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 55687-49-5
4-<(2,4-diamino-5-pyrimidinyl)methyl>-1,6-dimethoxybenzyl alcohol

: 74-88-4
methyl iodide

: 55687-86-0
2,4-diamino-5-<3,5-dimethoxy-4-(methoxymethyl)benzyl>-pyrimidine

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; for 2h; Ambient temperature;

Reference yield:

: 55687-85-9
α-(dimethoxymethyl)-3,5-dimethoxy-4-(methoxymethyl)-hydrocinnamic acid nitrile

: 50-01-1
guanidine hydrochloride

: 55687-86-0
2,4-diamino-5-<3,5-dimethoxy-4-(methoxymethyl)benzyl>-pyrimidine

Guidance literature:: In methanol; isopropyl alcohol;

Reference yield:

: 33187-98-3
3,5-dimethoxy-4-(methoxycarbonyl)benzaldehyde

: 55687-86-0
2,4-diamino-5-<3,5-dimethoxy-4-(methoxymethyl)benzyl>-pyrimidine

Guidance literature:: Multi-step reaction with 5 steps

1: 81 percent / sodium methylate / dimethylformamide / 0.25 h / 75 °C

2: 95 percent / propan-2-ol / 0.5 h / Heating

3: 86 percent / sodium methylate / ethanol / 40 h / Heating

4: 62 percent / dibal-H / dioxane / 1.25 h / 50 °C

5: 82 percent / sodium hydride / dimethylformamide / 2 h / Ambient temperature

With sodium methylate; sodium hydride; diisobutylaluminium hydride; In 1,4-dioxane; ethanol; N,N-dimethyl-formamide; isopropyl alcohol;