2-Piperidinone, 6-phenyl-1-(3-(4-((1-pyrrolidinylcarbonyl)methyl)-1-piperazinyl)propyl)-, ethanedioate (1:2)

Base Information

Chemical Name:2-Piperidinone, 6-phenyl-1-(3-(4-((1-pyrrolidinylcarbonyl)methyl)-1-piperazinyl)propyl)-, ethanedioate (1:2)
CAS No.:109758-37-4
Molecular Formula:C28H40N4O10
Molecular Weight:592.638
Hs Code.:
DSSTox Substance ID:DTXSID90911333
Mol file:109758-37-4.mol

Synonyms:M.G. 16248;109758-37-4;2-Piperidinone, 6-phenyl-1-(3-(4-((1-pyrrolidinylcarbonyl)methyl)-1-piperazinyl)propyl)-, ethanedioate (1:2);DTXSID90911333;C24H36N4O2.2C2H2O4;LS-117279;C24-H36-N4-O2.2C2-H2-O4;Oxalic acid--1-(3-{4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]piperazin-1-yl}propyl)-6-phenylpiperidin-2-one (2/1)

Suppliers and Price of 2-Piperidinone, 6-phenyl-1-(3-(4-((1-pyrrolidinylcarbonyl)methyl)-1-piperazinyl)propyl)-, ethanedioate (1:2)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Piperidinone, 6-phenyl-1-(3-(4-((1-pyrrolidinylcarbonyl)methyl)-1-piperazinyl)propyl)-, ethanedioate (1:2)

Chemical Property:

Vapor Pressure:1.01E-15mmHg at 25°C
Boiling Point:628.8°Cat760mmHg
Flash Point:275.2°C
Density:g/cm³
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:9
Exact Mass:592.27444349
Heavy Atom Count:42
Complexity:635

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C1)C(=O)CN2CCN(CC2)CCCN3C(CCCC3=O)C4=CC=CC=C4.C(=O)(C(=O)O)O.C(=O)(C(=O)O)O

Technology Process of 2-Piperidinone, 6-phenyl-1-(3-(4-((1-pyrrolidinylcarbonyl)methyl)-1-piperazinyl)propyl)-, ethanedioate (1:2)

There total 2 articles about 2-Piperidinone, 6-phenyl-1-(3-(4-((1-pyrrolidinylcarbonyl)methyl)-1-piperazinyl)propyl)-, ethanedioate (1:2) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 41419-25-4
6-phenylpiperidin-2-one

: 109758-37-4
1-{3-[4-(2-Oxo-2-pyrrolidin-1-yl-ethyl)-piperazin-1-yl]-propyl}-6-phenyl-piperidin-2-one; compound with oxalic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 26 percent / 80percent NaH / dimethylformamide / 3 h / Ambient temperature

2: 1.) KI, 2.) K₂CO₃ / 1.) isobutylmethylketone, reflux, 30 min, 2.) isobutylmethylketone, 48 h

With sodium hydride; potassium carbonate; potassium iodide; In N,N-dimethyl-formamide;

Reference yield:

: 144-62-7,97993-78-7
oxalic acid

: 109758-07-8
1-(3-ciclopropil)-6-fenil-piperidin-2-one

: 39890-45-4
1-[(pyrrolidine-1-carbonyl)methyl]piperazine

: 109758-37-4
1-{3-[4-(2-Oxo-2-pyrrolidin-1-yl-ethyl)-piperazin-1-yl]-propyl}-6-phenyl-piperidin-2-one; compound with oxalic acid

Guidance literature:: With potassium carbonate; potassium iodide; Yield given. Multistep reaction; 1.) isobutylmethylketone, reflux, 30 min, 2.) isobutylmethylketone, 48 h;