5,6-Dimethyl-2,3-dihydro-1H-indene-1-one

Base Information

• Chemical Name: 5,6-Dimethyl-2,3-dihydro-1H-indene-1-one
• CAS No.: 16440-97-4
• Molecular Formula: C11H12 O
• Molecular Weight: 160.216
• Hs Code.: 2914399090
• Mol file: 16440-97-4.mol

Synonyms:1-Indanone,5,6-dimethyl- (6CI,8CI); 5,6-Dimethyl-1-indanone

Chemical Property of 5,6-Dimethyl-2,3-dihydro-1H-indene-1-one

Chemical Property:

• Vapor Pressure: 0.00127mmHg at 25°C
• Boiling Point: 298.4°Cat760mmHg
• Flash Point: 127.4°C
• PSA: 17.07000
• Density: 1.085g/cm³
• LogP: 2.43230
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98% ^*data from raw suppliers

5,6-Dimethyl-1-indanone 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5,6-Dimethyl-2,3-dihydro-1H-indene-1-one

There total 22 articles about 5,6-Dimethyl-2,3-dihydro-1H-indene-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

3-(3,4-dimethylphenyl)propionic acid (25173-76-6) → 5,6-Dimethylindan-1-one (16440-97-4) + 6,7-dimethyl-2,3-dihydro-1H-inden-1-one (16440-98-5)

Guidance literature:

With phosphoric acid; phosphorus pentoxide; at 90 ℃; for 3h;

DOI:10.1002/jhet.5570240326

Reference yield: 40.0%

o-xylene (95-47-6) + 2-chloropropionyl chloride (625-36-5) → 5,6-Dimethylindan-1-one (16440-97-4)

Guidance literature:

With aluminum (III) chloride; In nitromethane; at 20 ℃; for 5h; Cooling with ice;

Reference yield: 40.0%

3-chloro-1-(3,4-dimethyl-phenyl)-propan-1-one (22422-23-7) → 5,6-Dimethylindan-1-one (16440-97-4)

Guidance literature:

With sulfuric acid; for 4h;

upstream raw materials:

3,4-dimethylbicyclo[4.3.0]non-3-en-9-one

5,6-dimethyl-3-oxo-indan-1-carboxylic acid

3-(3,4-dimethylphenyl)propionyl chloride

o-xylene

Refernces

• 1、 Chuang, Po-Yao,Okumura, Akira,Saito, Kodai,Yamada, Tohru. "Silver-Catalyzed Carbon Dioxide Fixation on Alkynylindenes". . . Retrieved 2020.
• 2、 -. "METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD". Paragraph 0147; 0254. . Retrieved 2015/11/03.