16440-98-5

Usage

Uses

Used in Flavor and Fragrance Industry:
6,7-DiMethyl-2,3-dihydro-1H-inden-1-one is used as a flavoring agent and odorant for adding a sweet, floral, and slightly woody aroma to various consumer products. Its unique scent profile contributes to the sensory characteristics of perfumes, cosmetics, and scented candles, enhancing the overall appeal of these products.
Used in Pharmaceutical Industry:
6,7-DiMethyl-2,3-dihydro-1H-inden-1-one has potential applications in the pharmaceutical industry as a flavoring agent, improving the taste and palatability of medications. Its sweet and floral notes can help mask the bitterness or unpleasant taste of certain drugs, making them more acceptable for patients to consume.
Used in Food Industry:
In the food industry, 6,7-DiMethyl-2,3-dihydro-1H-inden-1-one can be used as a flavoring agent to impart a sweet, floral, and slightly woody aroma to various food products. Its unique scent profile can enhance the sensory experience of food items, making them more enjoyable for consumers.

Upstream product

• 26801-37-6 3-(3,4-dimethylphenyl)propionyl chloride 
• 5973-71-7 3,4-dimethylbenzaldehyde 
• 50-00-0 formaldehyd 
• 108-59-8 malonic acid dimethyl ester 
• 603-79-2 2,3-dimethylbenzoic acid 
• 112631-49-9 3-(2-bromo-4,5-dimethylphenyl)propionic acid 
• 25173-76-6 3-(3,4-dimethylphenyl)propionic acid 
• 21900-46-9 2,3-dimethylbenzoyl chloride 
• 619-04-5 3,4-dimethylbenzoic acid 
• 38404-42-1 methyl 3,4-dimethylbenzoate 
• 147219-20-3 3-(3,4-Dimethylphenyl)-propensaeure 
• 6966-10-5 3,4-dimethylbenzyl alcohol 
• 112631-50-2 4-bromo-6,7-dimethyl-1-indanone 
• 112631-51-3 2-(2,3-dimethylbenzoyl)ethyl chloride 

Relevant academic research and scientific papers

Rh-Catalyzed Annulation of Benzoic Acids, Formaldehyde, and Malonates via ortho-Hydroarylation to Indanones

A three-component reaction from readily available low-cost materials of benzoic acids, formaldehyde, and malonates for the preparation of indanones by rhodium catalysis is reported. The annulation is initiated by an ortho-hydroarylation of benzoic acids, and a Lewis acid is not required. The solvent has a significant influence to the reaction, and 2-substituted or nonsubstituted indanones are obtained by the change of solvent.

SUBSTITUTED FLUOROETHYL UREAS AS ALPHA 2 ADRENERGIC AGENTS

Therapeutic compounds, and methods, compositions, and medicaments related thereto are disclosed herein.

Aromatic Spiranes XX [1]: Syntheses of Dimethylsubstituted 2-Carboxymethyl-indan-1-ones and Benzylchlorides as Synthones for Syntheses of di- to tetramethylsubstituted Spirobiindandiones

The isomeric dimethyl methylbenzoates 5, obtained from the bromides via Grignard reactions with dimethylcarbonate, were reduced with LiAlH4 to the hydroxymethyl derivatives 6. The latter were then transformed both to the benzylchlorides 7 (with SOCl2) and to the aldehydes 8 (with pyridinium chlorochromate). Knoevenagel-Doebner reaction of 8 afforded the acrylic acids 9 which (after hydrogenation to 11) were cyclized to the desired indanones 12 with polyphosphoric acid. On the other hand, 12c and 12e were prepared from dimethyl 3-chloropropiophenone (14) by warming with sulfuric acid. After NaH-catalyzed reaction with dimethylcarbonate, the indanones 12 gave the ketoesters 15 which then could be hydrogenated to the indanes 16. All reactions proceeded with satisfactory to excellent yields (60-90%).