bis(2-phenylethyl)propanedioic acid

Base Information

• Chemical Name: bis(2-phenylethyl)propanedioic acid
• CAS No.: 86310-45-4
• Molecular Formula: C19H20 O4
• Molecular Weight: 312.3597

Synonyms:Malonicacid, diphenethyl- (2CI); Propanedioic acid, bis(2-phenylethyl)- (9CI);Bis(2-Phenylethyl)malonic acid; NSC 211088

Chemical Property of bis(2-phenylethyl)propanedioic acid

Chemical Property:

• Vapor Pressure: 3.9E-10mmHg at 25°C
• Boiling Point: 482.9°Cat760mmHg
• Flash Point: 259.9°C
• Density: 1.225g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of bis(2-phenylethyl)propanedioic acid

There total 6 articles about bis(2-phenylethyl)propanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

→ diphenethyl-malonic acid (86310-45-4)

Guidance literature:

Reference yield:

aqueous diethyl ether + i-Amyl alcohol (123-51-3) + 1-phenyl-2-bromoethane (103-63-9) + diethyl malonate (105-53-3) → 2-(2-phenylethyl)-4-phenylbutanoic acid (17486-91-8) + diphenethyl-malonic acid (86310-45-4)

Guidance literature:

With hydrogenchloride; sodium hydroxide; In 1,2-dimethoxyethane; water;

Reference yield:

diethyl 2,2-diphenethylmalonate (34887-18-8) → diphenethyl-malonic acid (86310-45-4)

Guidance literature:

With potassium hydroxide; In ethanol;

DOI:10.1039/DT9920002679

upstream raw materials:

diethyl 2,2-diphenethylmalonate

1-phenyl-2-bromoethane

i-Amyl alcohol

diethyl malonate

Downstream raw materials:

2-(2-phenylethyl)-3,4-dihydro-2H-naphthalen-1-one

2-phenethyl-4-phenyl-butyric acid amide

2-phenethyl-4-phenyl-butyric acid-(2-diethylamino-ethyl ester)

2-phenethyl-4-phenyl-butyryl chloride

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