17486-91-8

Upstream product

• 17486-90-7 2-phenethyl-4-phenylbutyronitrile 
• 42929-48-6 2-phenethyl-4-phenylbutanal 
• 62115-07-5 Acetic acid 1-cyano-2-phenethyl-4-phenyl-but-1-enyl ester 
• 17486-88-3 2-phenethyl-4-phenylbutan-1-ol 
• 56-23-5 tetrachloromethane 
• 7732-18-5 water 
• 5396-91-8 1,5-diphenyl-3-pentanone 
• 34887-18-8 diethyl 2,2-diphenethylmalonate 
• 103-63-9 1-phenyl-2-bromoethane 
• 123-51-3 i-Amyl alcohol 
• 105-53-3 diethyl malonate 
• 59463-43-3 2-tert-Butoxy-3-phenethyl-5-phenyl-pent-2-enenitrile 
• 538-58-9 1,5-diphenyl-1,4-pentadiene-3-one 
• 17486-89-4 p-Toluolsulfonsaeure-(1,5-diphenyl-pentyl-3-ester) 

Downstream Products

• 62115-21-3 2-phenethyl-4-phenyl-butyric acid amide 
• 17486-92-9 2-(2-phenylethyl)-3,4-dihydro-2H-naphthalen-1-one 
• 18930-97-7 5,6,11,12-tetrahydrochrysene 
• 95622-95-0 2-phenethyl-4-phenyl-butyric acid anilide 
• 855215-89-3 2-phenethyl-4-phenyl-butyryl chloride 

Relevant academic research and scientific papers

BACTERIAL EFFLUX PUMP INHIBITORS

Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising of compounds of formula I and methods using compounds of formula I.

CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER

The invention provides novel compounds of formula (I), wherein: R1 is a radical derived from one of the known ring systems; R2 is a phenyl radical optionally substituted; Xn represents a birradical selected from the group consisting of: -(CH2)1-4-, (C2-C4)-alkenyl, (C2-C4)alkynyl, -S-(CH2)1-3-#, and -(CH2)1-3-O-#; wherein the symbol # indicates the position at which Xn is attached to R1; Yn is a birradical selected from the group consisting of: -(CH2)2-4-, -S-(CH2)1-3#, and -O-(CH2)1-3-#,; where in the symbol # indicates the position at which Yn is attached to R2; and R3 is a radical selected from the group consisting of: -OR4. The compounds of formula (I) are useful in the treatment of cancer

Dipeptides as renin inhibitors

Dipeptides are described which are represented by the formula STR1 wherein the various substituents are defined hereinbelow. These compounds have a strong inhibitory efect on human renin, and are useful as a therapeutically active agent for the treatment of hypertension, especially renin-associated hypertension.