11H-Dibenzo(b,e)(1,4)diazepin-11-one, 5-((bis(2-hydroxyethyl)amino)acetyl)-8-chloro-5,10-dihydro-, monohydrochloride

Base Information

Chemical Name:11H-Dibenzo(b,e)(1,4)diazepin-11-one, 5-((bis(2-hydroxyethyl)amino)acetyl)-8-chloro-5,10-dihydro-, monohydrochloride
CAS No.:98374-55-1
Molecular Formula:C₁₉H₂₀ClN₃O₄*ClH
Molecular Weight:426.299
Hs Code.:
DSSTox Substance ID:DTXSID70913315
Mol file:98374-55-1.mol

Synonyms:AWD 26-06;AWD-26-06

Suppliers and Price of 11H-Dibenzo(b,e)(1,4)diazepin-11-one, 5-((bis(2-hydroxyethyl)amino)acetyl)-8-chloro-5,10-dihydro-, monohydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 3 raw suppliers

Chemical Property of 11H-Dibenzo(b,e)(1,4)diazepin-11-one, 5-((bis(2-hydroxyethyl)amino)acetyl)-8-chloro-5,10-dihydro-, monohydrochloride

Chemical Property:

Vapor Pressure:3.81E-16mmHg at 25°C
Melting Point:225 °C
Boiling Point:618.3°Cat760mmHg
Flash Point:327.7°C
PSA：98.56000
Density:g/cm³
LogP:2.42720
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:425.0909115
Heavy Atom Count:28
Complexity:529

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)NC3=C(N2C(=O)CN(CCO)CCO)C=CC(=C3)Cl.Cl

Technology Process of 11H-Dibenzo(b,e)(1,4)diazepin-11-one, 5-((bis(2-hydroxyethyl)amino)acetyl)-8-chloro-5,10-dihydro-, monohydrochloride

There total 6 articles about 11H-Dibenzo(b,e)(1,4)diazepin-11-one, 5-((bis(2-hydroxyethyl)amino)acetyl)-8-chloro-5,10-dihydro-, monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 111-42-2
2,2'-iminobis[ethanol]

: 29174-50-3
8-chloro-5-chloroacetyl-5,10-dihydro-dibenzo[b,e][1,4]diazepin-11-one

: 98374-55-1
8-Chlor-5,10-dihydro-5--11H-dibenzo<1,4>-diazepin-11-on-hydrochlorid

Guidance literature:: With hydrogenchloride; In N,N-dimethyl-formamide; for 8h; Ambient temperature;

Reference yield:

: 67990-66-3
N-(2-Amino-4-chlorophenyl)anthranilic acid

: 98374-55-1
8-Chlor-5,10-dihydro-5--11H-dibenzo<1,4>-diazepin-11-on-hydrochlorid

Guidance literature:: Multi-step reaction with 3 steps

1: conc. H₃PO₄ / xylene / 140 °C

2: 90 percent / xylene / Heating

3: 70 percent / 2.) conc. HCl / dimethylformamide / 8 h / Ambient temperature

With hydrogenchloride; phosphoric acid; In N,N-dimethyl-formamide; xylene;

Reference yield:

: 60091-87-4
2-(4-Chlor-2-nitrophenyl)aminobenzencarbonsaeure

: 98374-55-1
8-Chlor-5,10-dihydro-5--11H-dibenzo<1,4>-diazepin-11-on-hydrochlorid

Guidance literature:: Multi-step reaction with 4 steps

1: 90 percent / DVP-Fe, conc. HCl / aq. ethanol; H₂O / Heating

2: conc. H₃PO₄ / xylene / 140 °C

3: 90 percent / xylene / Heating

4: 70 percent / 2.) conc. HCl / dimethylformamide / 8 h / Ambient temperature

With hydrogenchloride; phosphoric acid; In ethanol; water; N,N-dimethyl-formamide; xylene;