Acetamide, N-(4-(3-(4-phenyl-1-piperazinyl)propoxy)phenyl)-

Base Information

Chemical Name:Acetamide, N-(4-(3-(4-phenyl-1-piperazinyl)propoxy)phenyl)-
CAS No.:85868-52-6
Molecular Formula:C21H27N3O2
Molecular Weight:353.464
Hs Code.:
DSSTox Substance ID:DTXSID80235156
Wikidata:Q83117013

Synonyms:BRN 4561510;N-(4-(3-(4-Phenyl-1-piperazinyl)propoxy)phenyl)acetamide;85868-52-6;ACETAMIDE, N-(4-(3-(4-PHENYL-1-PIPERAZINYL)PROPOXY)PHENYL)-;DTXSID80235156;BDBM152520;N-[4-{3-(4-phenylpiperazin-1-yl)propoxy}phenyl]acetamide (2b)

Suppliers and Price of Acetamide, N-(4-(3-(4-phenyl-1-piperazinyl)propoxy)phenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Acetamide, N-(4-(3-(4-phenyl-1-piperazinyl)propoxy)phenyl)-

Chemical Property:

Vapor Pressure:1.52E-13mmHg at 25°C
Boiling Point:582.2°C at 760 mmHg
Flash Point:305.9°C
Density:1.146g/cm³
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:353.21032711
Heavy Atom Count:26
Complexity:410

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)NC1=CC=C(C=C1)OCCCN2CCN(CC2)C3=CC=CC=C3

Technology Process of Acetamide, N-(4-(3-(4-phenyl-1-piperazinyl)propoxy)phenyl)-

There total 4 articles about Acetamide, N-(4-(3-(4-phenyl-1-piperazinyl)propoxy)phenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 108-24-7
acetic anhydride

: 85868-46-8
1-<4-aminophenoxy>-3-1-(N⁴-phenylpiperazinyl)>propane

: 85868-52-6
1-(4-acetamidophenoxy)-3-1-(N⁴-phenylpiperazinyl)>propane

Guidance literature:: at 100 ℃; for 0.25h;

Reference yield: 77.4%

: 92-54-6
4-phenyl-1-piperazine

: 104800-03-5
1-[4-acetamidophenoxy]-3-chloropropane

: 85868-52-6
1-(4-acetamidophenoxy)-3-1-(N⁴-phenylpiperazinyl)>propane

Guidance literature:: With potassium carbonate; In butanone; at 90 - 100 ℃; for 30h; Green chemistry;
DOI:10.1016/j.bioorg.2015.04.004

Reference yield:

: 84344-45-6
1-(4-nitrophenoxy)-3-1-(N⁴-phenylpiperazinyl)>propane

: 85868-52-6
1-(4-acetamidophenoxy)-3-1-(N⁴-phenylpiperazinyl)>propane

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / H₂, Raney-nickel / ethanol / 4 h / 2585.7 Torr

2: 88 percent / 0.25 h / 100 °C

With hydrogen; nickel; In ethanol;