3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-furyl)-, dimethyl ester

Base Information

Chemical Name:3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-furyl)-, dimethyl ester
CAS No.:43114-35-8
Molecular Formula:C15H17NO5
Molecular Weight:291.304
Hs Code.:
DSSTox Substance ID:DTXSID60195704
Nikkaji Number:J85.648G
ChEMBL ID:CHEMBL1411734
Mol file:43114-35-8.mol

Synonyms:43114-35-8;BRN 0546601;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-furyl)-, dimethyl ester;dimethyl 4-(furan-2-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;2,6-Dimethyl-4-(2-furyl)-1,4-dihydro-3,5-pyridinedicarboxylic acid dimethyl ester;3,5-Pyridinedicarboxylic acid, 4-(2-furanyl)-1,4-dihydro-2,6-dimethyl-, 3,5-dimethyl ester;Oprea1_261752;Oprea1_362897;MLS000767345;CHEMBL1411734;SCHEMBL10500289;DTXSID60195704;HMS2788P13;CCG-15602;STK387365;AKOS000650523;4-Furan-2-yl-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester;NCGC00246377-01;SMR000429676;LS-131241;CS-0332309;EU-0001790;SR-01000393589;SR-01000393589-1;2,6-dimethyl-3,5-bis(methoxycarbonyl)-4-furyl-1,4-dihydropyridine;dimethyl 4-(2-furyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate;dimethyl 4-(2-furyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;1,4-Dihydro-2,6-dimethyl-4-(2-furyl)-3,5-pyridinedicarboxylic acid dimethyl ester

Suppliers and Price of 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-furyl)-, dimethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-furyl)-, dimethyl ester

Chemical Property:

PSA：77.77000
LogP:2.18920
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:291.11067264
Heavy Atom Count:21
Complexity:482

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CO2)C(=O)OC

Technology Process of 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-furyl)-, dimethyl ester

There total 4 articles about 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-furyl)-, dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 98-01-1
furfural

: 105-45-3
acetoacetic acid methyl ester

: 43114-35-8
4-furan-2-yl-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester

Guidance literature:: With ammonium acetate; barium(II) nitrate; at 20 ℃; for 0.25h;
DOI:10.1002/jhet.5570450316

Reference yield: 95.0%

: 98-01-1
furfural

: 105025-71-6
methoxy acetoacetate

: 43114-35-8
4-furan-2-yl-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester

Guidance literature:: With ammonium acetate; In neat (no solvent); at 60 ℃; for 0.333333h;
DOI:10.1039/c3ta12476b

Reference yield:

: 58-86-6
D-xylose

: 43114-35-8
4-furan-2-yl-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: Fe₃O₄/SiO₂-SO₃H / water / 4 h / 69.84 °C

2: ammonium acetate / neat (no solvent) / 1 h / 80 °C / Green chemistry

With ammonium acetate; In water; 2: |Hantzsch Dihydropyridine Synthesis;
DOI:10.1007/s10562-014-1267-8