Sulfoximine,S,S-diphenyl-

Base Information

• Chemical Name: Sulfoximine,S,S-diphenyl-
• CAS No.: 22731-83-5
• Molecular Formula: C12H11 N O S
• Molecular Weight: 217.291
• Mol file: 22731-83-5.mol

Synonyms:Diphenylsulfoximine; Diphenylsulfoximide; NSC 172172; S,S-Diphenylsulfoximide;S,S-Diphenylsulfoximine

Chemical Property of Sulfoximine,S,S-diphenyl-

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Sulfoximine,S,S-diphenyl-

There total 102 articles about Sulfoximine,S,S-diphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

methanol (67-56-1) + isopropyloxy(diphenyl)-λ6-sulfanenitrile (143885-03-4) → isopropyl methyl ether (598-53-8) + S,S-diphenylsulphoximine (22731-83-5)

Guidance literature:

at 45 ℃; for 114h;

DOI:10.1002/hc.20006

Reference yield: 99.0%

butyloxy(diphenyl)-λ6-sulfanenitrile (143885-04-5) → butan-1-[2H]ol (4712-38-3) + S,S-diphenylsulphoximine (22731-83-5)

Guidance literature:

With [D₃]acetonitrile; water-d2; In phosphate buffer; at 20 ℃; for 0.75h; pH=6.1; Further Variations:; pH-values; Reagents; Solvents; Temperatures; Kinetics; Thermodynamic data; Product distribution;

DOI:10.1246/bcsj.73.957

Reference yield: 99.0%

isopropyloxy(diphenyl)-λ6-sulfanenitrile (143885-03-4) → Isopropanol-d1 (3979-51-9) + S,S-diphenylsulphoximine (22731-83-5)

Guidance literature:

With [D₃]acetonitrile; water-d2; In various solvent(s); at 20 ℃; for 0.333333h; pH=8.7; Further Variations:; pH-values; Reagents; Solvents; Temperatures; Kinetics; Thermodynamic data; Product distribution;

DOI:10.1246/bcsj.73.957

upstream raw materials:

chloroform

1,1'-sulfinylbisbenzene

piperidine

S,S-diphenyl-N-(4-methylphenylthio)sulfoximine

Downstream raw materials:

(Z)-N-(1,2-Dimethoxycarbonylvinyl)-diphenylsulfoximin

1,1'-sulfinylbisbenzene

N,N'-bis(p-toluenesulfonyl)hydroxylamine

bis(4-methylphenylsulfonyl)amino 4-methylbenzenesulfonate

Refernces

• 1、 Hommelsheim, Renè,Nú?ez Ponce, Heliana Michaela,Truong, Khai-Nghi,Rissanen, Kari,Bolm, Carsten. "2-Sulfoximidoyl acetic acids from multicomponent petasis reactions and their use as building blocks in syntheses of sulfoximine benzodiazepine analogues". . p. 3415 - 3420. Retrieved 2021/05/04.
• 2、 Zupanc, An?e,Jereb, Marjan. "One-Pot Synthesis of N-Iodo Sulfoximines from Sulfides". . p. 5991 - 6000. Retrieved 2021/05/05.