5-(4-Methoxyphenyl)thiophene-2-carbaldehyde

Base Information

• Chemical Name: 5-(4-Methoxyphenyl)thiophene-2-carbaldehyde
• CAS No.: 38401-67-1
• Molecular Formula: C13H12O2S
• Molecular Weight: 218.276
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID90383955
• Nikkaji Number: J2.255.572C
• Wikidata: Q82175792
• Mol file: 38401-67-1.mol

Synonyms:5-(4-methoxyphenyl)thiophene-2-carbaldehyde;38401-67-1;5-(4-methoxyphenyl)-2-thiophenecarbaldehyde;5-(4-Methoxyphenyl)thiophene-2-carboxaldehyde;SCHEMBL1133663;DTXSID90383955;ODLOZSNXTQAWGQ-UHFFFAOYSA-N;GEO-03577;MFCD00663639;2,4,5-TRIMETHOXYBENZYLALCOHOL;AKOS004117707;2-formyl-5-(4-methoxyphenyl)thiophene;AB06670;BB 0222854;CS-0314057;FT-0639463;5-(4-methoxylphenyl)thiophene-2-carbaldehyde;5-(4-Methoxy-phenyl)-thiophene-2-carbaldehyde;A824136;10X-0704;J-516262;5-(4-Methoxyphenyl)thiophene-2-carbaldehyde, AldrichCPR

Chemical Property of 5-(4-Methoxyphenyl)thiophene-2-carbaldehyde

Chemical Property:

• Vapor Pressure: 7.57E-06mmHg at 25°C
• Melting Point: 118oC
• Boiling Point: 375.8°C at 760 mmHg
• Flash Point: 181.1°C
• PSA: 54.54000
• Density: 1.213g/cm³
• LogP: 3.23620
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 218.04015073
• Heavy Atom Count: 15
• Complexity: 212

Purity/Quality:

97% ^*data from raw suppliers

5-(4-Methoxyphenyl)-2-thiophenecarbaldehyde >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C2=CC=C(S2)C=O

Technology Process of 5-(4-Methoxyphenyl)thiophene-2-carbaldehyde

There total 15 articles about 5-(4-Methoxyphenyl)thiophene-2-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

5-bromo-2-thiophencarboxaldehyde (4701-17-1) + 4-methoxyphenylboronic acid (5720-07-0) → 2-formyl-5-(4-methoxyphenyl)thiophene (38401-67-1)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In ethanol; water; toluene; for 4h; Inert atmosphere; Reflux;

Reference yield: 87.7%

2-bromo-1,3-thiazole-5-carbaldehyde (464192-28-7) + 4-methoxyphenylboronic acid (5720-07-0) → 2-formyl-5-(4-methoxyphenyl)thiophene (38401-67-1)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In ethanol; water; toluene; at 60 ℃; for 5h; Inert atmosphere;

Reference yield: 83.0%

5-bromo-2-thiophencarboxaldehyde (4701-17-1) + 4-methoxyphenyl magnesium bromide (13139-86-1) → 2-formyl-5-(4-methoxyphenyl)thiophene (38401-67-1) + [2,2']bithiophenyl-5,5'-dicarbaldehyde (32364-72-0) + 4,4'-Dimethoxybiphenyl (2132-80-1)

Guidance literature:

4-methoxyphenyl magnesium bromide; With bismuth(III) chloride;

5-bromo-2-thiophencarboxaldehyde; With potassium phosphate; palladium diacetate; triphenylphosphine; In N,N-dimethyl-formamide; at 90 ℃; for 1h; Inert atmosphere;

DOI:10.1055/s-0030-1260554

upstream raw materials:

2-(4-methoxyphenyl)thiophene

N,N-dimethyl-formamide

5-bromo-2-thiophencarboxaldehyde

4-methoxyphenylboronic acid

Downstream raw materials:

2-(4-{(E)-2-[5-(4-Methoxy-phenyl)-thiophen-2-yl]-vinyl}-phenyl)-5-phenyl-oxazole

2-dicyanovinyl-5-(4-methoxyphenyl)thiophene

2-(4-{(E)-2-[5-(4-Methoxy-phenyl)-thiophen-2-yl]-vinyl}-phenyl)-5-phenyl-[1,3,4]oxadiazole

(E)-3-[5-(4-methoxyphenyl)-2-thienyl]acrylic acid chloride

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 38401-67-1 5-(4-methoxyphenyl)thiophene-2-carbaldehyde

Send

Send

Metric Ton KG G Pound L ML

Send

Send