6-METHYLAMINOURACIL

Base Information

• Chemical Name: 6-METHYLAMINOURACIL
• CAS No.: 34284-87-2
• Molecular Formula: C5H7N3O2
• Molecular Weight: 141.129
• Hs Code.: 2933599090
• Mol file: 34284-87-2.mol

Synonyms:NSC 81005;6-Methylaminouracil;6-(Methylamino)-2,4(1H,3H)-pyrimidinedione;Uracil,6-(methylamino)- (6CI,7CI,8CI);

Chemical Property of 6-METHYLAMINOURACIL

Chemical Property:

• Melting Point: 300-302℃
• Refractive Index: 1.569
• PSA: 77.75000
• Density: 1.36 g/cm³
• LogP: -0.82210
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

6-Methylamino-1H-pyrimidine-2,4-dione 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-METHYLAMINOURACIL

There total 7 articles about 6-METHYLAMINOURACIL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

6-chlorouracil (4270-27-3) + methylamine (74-89-5) → 6-(methylamino)pyrimidine-2,4(1H,3H)-dione (34284-87-2)

Guidance literature:

for 2h; Reflux;

DOI:10.2174/1573406411309040012

Reference yield:

9-methyluric acid (55441-71-9) → 6-(methylamino)pyrimidine-2,4(1H,3H)-dione (34284-87-2)

Guidance literature:

With ethylenediaminetetraacetic acid; nitrogen(II) oxide; In phosphate buffer; pH=7.4;

DOI:10.1080/15257770802257952

Reference yield:

(2,6-bis-benzyloxy-pyrimidin-4-yl)-methyl-amine (856974-71-5) → 6-(methylamino)pyrimidine-2,4(1H,3H)-dione (34284-87-2)

Guidance literature:

With palladium on activated charcoal; acetic acid;

DOI:10.1039/jr9470000726

upstream raw materials:

6-chlorouracil

methylamine

(2,6-bis-benzyloxy-pyrimidin-4-yl)-methyl-amine

(2,6-dichloro-pyrimidin-4-yl)-methyl-amine

Downstream raw materials:

5,5'-<4'-nitro-1,1'-biphenyl>-4-ylmethylenebis(6-methylaminouracil)

5,5'-p-chlorophenylmethylenebis(6-methylaminouracil)

5,5'-p-nitrophenylmethylenebis(6-methylaminouracil)

5,5'-<4'-chloro-1,1'-biphenyl>-4-ylmethylenebis(6-methylaminouracil)

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