4,5,6,7-Tetrahydroazepino(3,2,1-hi)indole-1,2-dione

Base Information

Chemical Name:4,5,6,7-Tetrahydroazepino(3,2,1-hi)indole-1,2-dione
CAS No.:4425-15-4
Molecular Formula:C12H11NO2
Molecular Weight:201.2212
Hs Code.:
NSC Number:100961
DSSTox Substance ID:DTXSID90963195

Synonyms:4425-15-4;4,5,6,7-Tetrahydroazepino(3,2,1-hi)indole-1,2-dione;NSC100961;NSC 100961;4,5,6,7-Tetrahydroazepino[3,2,1-hi]indole-1,2-dione;SCHEMBL749609;DTXSID90963195;NSC-100961;1-azatricyclo[6.4.1.04,13]trideca-4,6,8(13)-triene-2,3-dione

Suppliers and Price of 4,5,6,7-Tetrahydroazepino(3,2,1-hi)indole-1,2-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 4,5,6,7-Tetrahydroazepino(3,2,1-hi)indole-1,2-dione

Chemical Property:

Vapor Pressure:1.19E-05mmHg at 25°C
Boiling Point:369.4°C at 760 mmHg
Flash Point:175.7°C
Density:1.33g/cm³
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:201.078978594
Heavy Atom Count:15
Complexity:313

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCN2C3=C(C1)C=CC=C3C(=O)C2=O

Technology Process of 4,5,6,7-Tetrahydroazepino(3,2,1-hi)indole-1,2-dione

There total 11 articles about 4,5,6,7-Tetrahydroazepino(3,2,1-hi)indole-1,2-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.69%

: 34849-23-5
oxo-(2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetyl chloride

: 4425-15-4
4,5,6,7-tetrahydro-azepino[3,2,1-hi]indole-1,2-dione

Guidance literature:: With aluminum (III) chloride; In carbon disulfide; at 20 ℃; Heating / reflux;

Reference yield:

: 1701-57-1
2,3,4,5-tetrahydro-1Hbenzo[b]azepine

: 79-37-8
oxalyl dichloride

: 4425-15-4
4,5,6,7-tetrahydro-azepino[3,2,1-hi]indole-1,2-dione

Guidance literature:: aluminium chloride; In tetrahydrofuran; carbon disulfide; ice-water;

Reference yield:

: 20642-90-4
1-methyl-2,3,4,5-tetrahydro-1H-benzo[b]azepine

: 4425-15-4
4,5,6,7-tetrahydro-azepino[3,2,1-hi]indole-1,2-dione

Guidance literature:: Multi-step reaction with 2 steps

1: cyanogen bromide / Erhitzen des erhaltenen 2,3,4,5-Tetrahydro-benz<b>azepin-1-carbonitrils mit konz. wss. Salzsaeure

2: hydroxylamine hydrochloride; sodium sulfate; water / Reagens 4: Salzsaeure; und Erwaermen des Reaktionsprodukts mit konz.Schwefelsaeure

With bromocyane; hydroxylamine hydrochloride; water; sodium sulfate;
DOI:10.1021/ja01620a034