Formamide,N,N'-1,3-phenylenebis- (9CI)

Base Information

• Chemical Name: Formamide,N,N'-1,3-phenylenebis- (9CI)
• CAS No.: 25227-79-6
• Molecular Formula: C8H8 N2 O2
• Molecular Weight: 164.164
• Mol file: 25227-79-6.mol

Synonyms:Formamide,N,N'-m-phenylenebis- (8CI); 1,3-Diformamidobenzene;N,N'-Diformyl-m-phenylenediamine; NSC 294824

Chemical Property of Formamide,N,N'-1,3-phenylenebis- (9CI)

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Formamide,N,N'-1,3-phenylenebis- (9CI)

There total 4 articles about Formamide,N,N'-1,3-phenylenebis- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

formic acid (64-18-6) + m-phenylenediamine (108-45-2,64554-26-3,76583-20-5) → N,N'-1,3-diaminobenzene-bis-formamide (25227-79-6)

Guidance literature:

With aminoproplylated mesoporous SBA-15 silica; at 40 ℃; for 0.5h; chemoselective reaction; Neat (no solvent);

DOI:10.1135/cccc2011131

Reference yield: 82.0%

formic acid (64-18-6) + m-phenylenediamine (108-45-2,64554-26-3,76583-20-5) + benzyl alcohol (100-51-6,185532-71-2) → benzyl formate (104-57-4) + N,N'-1,3-diaminobenzene-bis-formamide (25227-79-6)

Guidance literature:

With aminopropylated mesoporous SBA-15 silica; at 40 ℃; for 2.5h; chemoselective reaction; Neat (no solvent);

DOI:10.1135/cccc2011131

Reference yield:

m-phenylenediamine (108-45-2,64554-26-3,76583-20-5) + formyl acetic anhydride (2258-42-6) → N,N'-1,3-diaminobenzene-bis-formamide (25227-79-6)

Guidance literature:

In tetrahydrofuran; at -10 ℃;

DOI:10.1016/j.tet.2011.08.085

upstream raw materials:

formic acid

m-phenylenediamine

formyl acetic anhydride

benzyl alcohol

Downstream raw materials:

N,N'-diformyl-N,N'-m-phenylene-di-β-alanine dinitrile

C₂₀H₁₈N₄O₂

1,3-bis(N-methylacetamido)benzene

N,N'-dimethyl-1,3-phenylenediamine