N1,N3-DiMethylbenzene-1,3-diaMine

Base Information

• Chemical Name: N1,N3-DiMethylbenzene-1,3-diaMine
• CAS No.: 14814-75-6
• Molecular Formula: C8H12N2
• Molecular Weight: 136.197
• Hs Code.: 2921519090
• Mol file: 14814-75-6.mol

Synonyms:N,N'-dimethyl-1,3-benzenediamine;N,N'-dimethyl-1,3-phenylenediamine;N,N-dimethyl-m-phenylenediamine;N1,N3-Dimethylbenzene-1,3-diamine;N,N'-dimethyl-1,3-diaminobenzene;N,N'-dimethylbenzene-1,3-diamine;InChI=1/C8H12N2/c1-9-7-4-3-5-8(6-7)10-2/h3-6,9-10H,1-2H;1,3-Benzenediamine, N,N‘-dimethyl-;

Chemical Property of N1,N3-DiMethylbenzene-1,3-diaMine

Chemical Property:

• Boiling Point: 85-86 °C(Press: 1 Torr)
• PKA: 5.60±0.25(Predicted)
• PSA: 24.06000
• Density: 1.061±0.06 g/cm3(Predicted)
• LogP: 1.91600
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

99.0% ^*data from raw suppliers

N,N''-Dimethylbenzene-1,3-diamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N1,N3-DiMethylbenzene-1,3-diaMine

There total 9 articles about N1,N3-DiMethylbenzene-1,3-diaMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

tert-butyl N-(3-{[(tert-butoxy)carbonyl]amino}phenyl)carbamate (59255-77-5) → N,N'-dimethyl-1,3-phenylenediamine (14814-75-6)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; Reflux;

DOI:10.1039/c2nj40567a

Reference yield: 90.0%

methanol (67-56-1) + m-phenylenediamine (108-45-2,64554-26-3,76583-20-5) → N,N'-dimethyl-1,3-phenylenediamine (14814-75-6)

Guidance literature:

With [((5-Me)PyNPPh₂)IrACHTUNGTRENUNG(cod)]; potassium tert-butylate; In diethylene glycol dimethyl ether; at 70 ℃; for 48h; Inert atmosphere;

DOI:10.1002/adsc.201100554

Reference yield: 83.0%

3-chloro-N-methylaniline (7006-52-2) + methylamine (74-89-5) → N,N'-dimethyl-1,3-phenylenediamine (14814-75-6)

Guidance literature:

With bis[chloro(1,2,3-trihapto-allylbenzene)palladium(II)]; N-[2-(di(1-adamantyl)phosphino)phenyl]morpholine; sodium t-butanolate; In tetrahydrofuran; toluene; at 85 ℃; for 21h; chemoselective reaction; Inert atmosphere;

DOI:10.1021/jo202358p

upstream raw materials:

formic acid

N-methyl-m-phenylenediamine

methyllithium

m-phenylenediamine

Downstream raw materials:

N,N'-dimethyl-2,4,6,N,N'-pentanitro-m-phenylenediamine

1,3,1',3'-tetramethyl-1,1'-m-phenylene-bis-thiourea

N,N'-diallyl-N,N'-dimethyl-1,3-benzenediamine

C₂₂H₁₈I₂N₂O₂