1-Stearoyllysophosphatidylcholine

Base Information

• Chemical Name: 1-Stearoyllysophosphatidylcholine
• CAS No.: 5655-17-4
• Molecular Formula: C₂₆H₅₄NO₇P
• Molecular Weight: 523.691
• Mol file: 5655-17-4.mol

Synonyms:3,5,9-Trioxa-4-phosphaheptacosan-1-aminium,4,7-dihydroxy-N,N,N-trimethyl-10-oxo-, inner salt, 4-oxide, (?à)-; Choline, hydroxide,dihydrogen phosphate, inner salt, 3-ester with 1-monostearin, DL- (8CI);1-Octadecanoyl-3-glycerophosphorylcholine;1-Stearoyl-2-lysophosphatidylcholine; 1-Stearoyl-3-glycerylphosphorylcholine;1-Stearoylglycero-3-phosphorylcholine; 1-Stearoyllysophosphatidylcholine;Stearoyl lysolecithin; Stearoyl lysophosphatidylcholine

Chemical Property of 1-Stearoyllysophosphatidylcholine

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 114.93000
• Density: g/cm³
• LogP: 6.43000

Purity/Quality:

99% ^*data from raw suppliers

1-STEAROYLLYSOPHOSPHATIDYLCHOLINE 95.00% ^*data from reagent suppliers

Safty Information:

• Safety Statements: Mutation data reported. When heated to decomposition it emits toxic vapors of NOx and POx.:;"> x and POx." target="_blank">Mutation data reported. When heated to decomposition it emits toxic vapors of NOx and POx.:

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Stearoyllysophosphatidylcholine

There total 23 articles about 1-Stearoyllysophosphatidylcholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

distearoylphosphatidylcholine (816-94-4,18603-43-5) → 1-stearoyl-sn-glycero-3-phosphocholine (19420-57-6,5655-17-4)

Guidance literature:

With tris hydrochloride; sodium docusate; calcium chloride; In 2,2,4-trimethylpentane; at 40 ℃; for 0.5h; pH=8.5; Enzymatic reaction;

DOI:10.1071/CH14606

Reference yield: 97.0%

L-glycero-3-phosphorylcholine (28319-77-9,563-24-6) + Stearoyl chloride (112-76-5) → 1-stearoyl-sn-glycero-3-phosphocholine (19420-57-6,5655-17-4)

Guidance literature:

L-glycero-3-phosphorylcholine; With di(n-butyl)tin oxide; In isopropyl alcohol; for 1h; Heating;

Stearoyl chloride; With TEA; In isopropyl alcohol; at 20 ℃; for 0.583333h; Further stages.;

DOI:10.1039/b604636c

Reference yield: 90.0%

{2-[(2,3-bis-stearoyloxy-propoxy)-hydroxy-phosphoryloxy]-ethyl}-trimethyl-ammonium betaine (816-94-4,4539-70-2,66701-63-1,816-93-3,18603-43-5) → 1-stearoyl-sn-glycero-3-phosphocholine (17364-19-1,5655-17-4)

Guidance literature:

With calcium chloride; In diethyl ether; at 29 ℃; for 3h; phospholipase A₂, 0.1 M pH 7.2 Tris buffer;

DOI:10.1002/mrc.1270180211

upstream raw materials:

rac.-1-Stearoyl-glycerin-benzylether-⁽²⁾-phosphorsaeure-⁽³⁾-monocholinester

{2-[(2,3-bis-stearoyloxy-propoxy)-hydroxy-phosphoryloxy]-ethyl}-trimethyl-ammonium betaine

glycerolcholine phosphate

1-octadecanoyl-1H-imidazole

Downstream raw materials:

1-octadecanoyl-2-[cis-9,12]-octadecadienoyl-glycero-3-phosphocholine

1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine

trimethyl (2-{[(2R)-2-[(9Z,12Z)-octadeca-9,12-dienoyloxy]-3-(octadecanoyloxy)propylphosphonato]oxy}ethyl)azanium

1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine