Chemical Property of 2,3-Dimethoxy-1,4-naphthoquinone
Chemical Property:
- Vapor Pressure:2.28E-06mmHg at 25°C
- Boiling Point:392.5°C at 760 mmHg
- Flash Point:177.6°C
- PSA：52.60000
- Density:1.28g/cm3
- LogP:1.57000
- Storage Temp.:−20°C
- Solubility.:Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 5 mg/ml).
- XLogP3:1.9
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:4
- Rotatable Bond Count:2
- Exact Mass:218.05790880
- Heavy Atom Count:16
- Complexity:322
- Purity/Quality:
-
99%, *data from raw suppliers
DMNQ *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xi
- Hazard Codes:Xi
- Statements:
36/37/38
- Safety Statements:
26-36
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:COC1=C(C(=O)C2=CC=CC=C2C1=O)OC
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Description
DMNQ is a 1,4-naphthoquinone that acts as a redox-cycling agent, typically increasing intracellular superoxide and hydrogen peroxide formation. The amount of oxidative stress is proportional to the amount of DMNQ applied and can alter diverse cellular parameters, including signal transduction, mitochondrial function, and gene expression.
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Uses
DMNQ is a non-alkylating redox cycling quinone. 2,3-Dimethoxy-1,4-naphthoquinone has been used to investigate the effects of ethanol on podocyte apoptosis under hypoxic and hyperoxic conditions.
