4-(5-p-Chlorophenylisoxazol-3-yl)phenylacetate

Base Information

Chemical Name:4-(5-p-Chlorophenylisoxazol-3-yl)phenylacetate
CAS No.:78868-48-1
Molecular Formula:C₁₈H₁₄ClNO₃
Molecular Weight:327.767
Hs Code.:
DSSTox Substance ID:DTXSID601000100
Wikidata:Q82993488

Synonyms:BRN 4521075;4-(5-p-Chlorophenylisoxazol-3-yl)phenylacetate;78868-48-1;Benzeneacetic acid, 4-(5-(4-chlorophenyl)-3-isoxazolyl)-, methyl ester;DTXSID601000100;LS-28699;Methyl {4-[5-(4-chlorophenyl)-1,2-oxazol-3-yl]phenyl}acetate

Suppliers and Price of 4-(5-p-Chlorophenylisoxazol-3-yl)phenylacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-(5-p-Chlorophenylisoxazol-3-yl)phenylacetate

Chemical Property:

Vapor Pressure:1.57E-09mmHg at 25°C
Boiling Point:484.2°C at 760 mmHg
Flash Point:246.6°C
Density:1.256g/cm³
XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:327.0662210
Heavy Atom Count:23
Complexity:390

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)CC1=CC=C(C=C1)C2=NOC(=C2)C3=CC=C(C=C3)Cl

Technology Process of 4-(5-p-Chlorophenylisoxazol-3-yl)phenylacetate

There total 5 articles about 4-(5-p-Chlorophenylisoxazol-3-yl)phenylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 67-56-1
methanol

: 78868-40-3
4-(5-p-Chlorophenylisoxazol-3-yl)phenylacetic acid

: 78868-48-1
Methyl 4-(5-p-chlorophenylisoxazol-3-yl)phenylacetate

Guidance literature:: With sulfuric acid; for 4h; Heating;

Reference yield:

: 7398-52-9
4-acetyl-phenylacetic acid

: 78868-48-1
Methyl 4-(5-p-chlorophenylisoxazol-3-yl)phenylacetate

Guidance literature:: Multi-step reaction with 4 steps

1: 65 percent / 40percent aq. NaOH / ethanol / 0.5 h / Ambient temperature

2: 80 percent / bromine / diethyl ether / 10 °C

3: 65 percent / NH₂OH*HCl, 40percent aq. NaOH / methanol / 2 h / Heating

4: 70 percent / conc. H₂SO₄ / 4 h / Heating

With sodium hydroxide; sulfuric acid; hydroxylamine hydrochloride; bromine; In methanol; diethyl ether; ethanol;

Reference yield:

: 104-88-1
4-chlorobenzaldehyde

: 78868-48-1
Methyl 4-(5-p-chlorophenylisoxazol-3-yl)phenylacetate

Guidance literature:: Multi-step reaction with 4 steps

1: 65 percent / 40percent aq. NaOH / ethanol / 0.5 h / Ambient temperature

2: 80 percent / bromine / diethyl ether / 10 °C

3: 65 percent / NH₂OH*HCl, 40percent aq. NaOH / methanol / 2 h / Heating

4: 70 percent / conc. H₂SO₄ / 4 h / Heating

With sodium hydroxide; sulfuric acid; hydroxylamine hydrochloride; bromine; In methanol; diethyl ether; ethanol;