2-chloro-N-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]acetamide

Base Information

Chemical Name:2-chloro-N-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]acetamide
CAS No.:83558-09-2
Molecular Formula:C11H8 Cl F N2 O S
Molecular Weight:270.715
Hs Code.:2934100090
European Community (EC) Number:856-525-8
DSSTox Substance ID:DTXSID90360665
Wikidata:Q82142523
Mol file:83558-09-2.mol

Synonyms:83558-09-2;2-chloro-N-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]acetamide;2-Chloro-N-[4-(4-fluoro-phenyl)-thiazol-2-yl]-acetamide;2-Chloro-N-(4-(4-fluorophenyl)thiazol-2-yl)acetamide;C11H8ClFN2OS;2-chloro-n-(4-(4-fluorophenyl)-1,3-thiazol-2-yl)acetamide;Acetamide,2-chloro-N-[4-(4-fluorophenyl)-2-thiazolyl]-;DTXSID90360665;2-bromo-2-cyclohexylacetyl chloride;MFCD01315354;AKOS000115577;5K-597S;CS-0062056;EN300-02041;W17888;Z56896301

Suppliers and Price of 2-chloro-N-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-Chloro-N-[4-(4-fluoro-phenyl)-thiazol-2-yl]-acetamide
1g
$ 378.00

Crysdot
2-Chloro-N-(4-(4-fluorophenyl)thiazol-2-yl)acetamide 95+%
5g
$ 874.00

Chemenu
2-Chloro-N-[4-(4-fluoro-phenyl)-thiazol-2-yl]-acetamide 95%
5g
$ 825.00

American Custom Chemicals Corporation
2-CHLORO-N-[4-(4-FLUORO-PHENYL)-THIAZOL-2-YL]-ACETAMIDE 95.00%
5G
$ 1548.26

American Custom Chemicals Corporation
2-CHLORO-N-[4-(4-FLUORO-PHENYL)-THIAZOL-2-YL]-ACETAMIDE 95.00%
2.5G
$ 1227.82

American Custom Chemicals Corporation
2-CHLORO-N-[4-(4-FLUORO-PHENYL)-THIAZOL-2-YL]-ACETAMIDE 95.00%
1G
$ 852.55

AK Scientific
2-Chloro-N-[4-(4-fluoro-phenyl)-thiazol-2-yl]-acetamide
1g
$ 503.60

Total 14 raw suppliers

Chemical Property of 2-chloro-N-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]acetamide

Chemical Property:

Melting Point:135℃ (ethanol )
PSA：70.23000
Density:1.454g/cm³
LogP:3.19950
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:270.0029899
Heavy Atom Count:17
Complexity:274

Purity/Quality:

98%min ^*data from raw suppliers

2-Chloro-N-[4-(4-fluoro-phenyl)-thiazol-2-yl]-acetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CSC(=N2)NC(=O)CCl)F

Technology Process of 2-chloro-N-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]acetamide

There total 3 articles about 2-chloro-N-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 79-04-9
chloroacetyl chloride

: 77815-14-6
2-amino-4-(4-fluorophenyl)thiazole

: 83558-09-2
2-chloro-N-(4-(4-fluorophenyl)thiazol-2-yl)acetamide

Guidance literature:: In benzene; for 3h; Heating;

Reference yield:

: 403-42-9
1-(4-fluorophenyl)ethanone

: 83558-09-2
2-chloro-N-(4-(4-fluorophenyl)thiazol-2-yl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: I₂

2: 80 percent / benzene / 3 h / Heating

With iodine; In benzene;

Reference yield:

: 403-29-2
2-bromo-4'-fluoroacetophenone

: 83558-09-2
2-chloro-N-(4-(4-fluorophenyl)thiazol-2-yl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 2 h / Reflux

2: triethylamine / N,N-dimethyl-formamide / 10 °C

With triethylamine; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2012.03.006