BUTYLSUCCINIC ANHYDRIDE

Base Information

• Chemical Name: BUTYLSUCCINIC ANHYDRIDE
• CAS No.: 2035-76-9
• Molecular Formula: C8H12O3
• Molecular Weight: 156.181
• Hs Code.: 2917190090
• Mol file: 2035-76-9.mol

Synonyms:Succinicanhydride, butyl- (7CI);1,2-Hexanedicarboxylic anhydride;3-Butyldihydro-2,5-furandione;Butylsuccinic anhydride;NSC 37761;n-Butylsuccinic anhydride;

Chemical Property of BUTYLSUCCINIC ANHYDRIDE

Chemical Property:

• Vapor Pressure: 0.00729mmHg at 25°C
• Melting Point: 46 °C
• Refractive Index: 1.455
• Boiling Point: 269.3 °C at 760 mmHg
• Flash Point: 121 °C
• PSA: 43.37000
• Density: 1.089 g/cm³
• LogP: 1.26630
• Storage Temp.: 0-10°C
• Solubility.: soluble in Toluene

Purity/Quality:

98%,99%, ^*data from raw suppliers

ButyisuccinicAnhydride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BUTYLSUCCINIC ANHYDRIDE

There total 7 articles about BUTYLSUCCINIC ANHYDRIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

→ 3-butyldihydrofuran-2,5-dione (2035-76-9)

Guidance literature:

With [(tetra(4-chlorophenyl)porphyrinato)aluminium(III)bis(tetrahydrofuran)][tetracarbonylcobaltate]; In 1,4-dioxane; at 90 ℃; for 3h; under 43958.7 Torr;

Reference yield: 96.0%

n-butylsuccinic acid (1457-39-2) → 3-butyldihydrofuran-2,5-dione (2035-76-9)

Guidance literature:

With acetyl chloride; for 3h; Heating;

DOI:10.1055/s-2000-7110

Reference yield: 65.0%

carbon monoxide (201230-82-2) + hex-1-yne (693-02-7) → 3-n-butylmaleic anhydride (100378-66-3) + 3-butyldihydrofuran-2,5-dione (2035-76-9) + 4-n-butyl-2(5H)furan-2-one (54145-06-1) + 3-n-butyl-2(5H)-furanone (71725-42-3)

Guidance literature:

With water; potassium iodide; palladium(II) iodide; In 1,4-dioxane; at 80 ℃; for 15h; under 7600 Torr;

DOI:10.1016/S0040-4039(98)02464-2

upstream raw materials:

n-butylsuccinic acid

carbon monoxide

hex-1-yne

1,2-Epoxyhexane

Downstream raw materials:

4-[2-(3-butyl-2,5-dioxo-pyrrolidin-1-yl)-3-methyl-butyryl]-morpholine

N-benzyloxy-2-butyl-succinamic acid

N⁴-benzyloxy-2-butyl-N¹-[2-methyl-1-(morpholine-4-carbonyl)-propyl]-succinamide

2-{[7-(4-cyclobutylthiazol-2-yl)naphthalen-2-ylcarbamoyl]methyl}hexanoic acid

Refernces

• 1、 Herron, Alastair N.,Yu, Jin-Quan,Zhuang, Zhe. "Synthesis of Cyclic Anhydrides via Ligand-Enabled C–H Carbonylation of Simple Aliphatic Acids". supporting information. p. 16382 - 16387. Retrieved 2021/06/23.
• 2、 Rowley, John M.,Lobkovsky, Emil B.,Coates, Geoffrey W.. "Catalytic double carbonylation of epoxides to succinic anhydrides: Catalyst discovery, reaction scope, and mechanism". . p. 4948 - 4960. Retrieved 2008/02/03.