1,2-Epoxyhexane

Base Information

• Chemical Name: 1,2-Epoxyhexane
• CAS No.: 1436-34-6
• Molecular Formula: C6H12 O
• Molecular Weight: 100.161
• Hs Code.: 29109000
• European Community (EC) Number: 215-864-6
• NSC Number: 246211,24268
• DSSTox Substance ID: DTXSID10870872
• Nikkaji Number: J73.698H
• Wikidata: Q104386482
• Mol file: 1436-34-6.mol

Synonyms:1,2-epoxyhexane

Chemical Property of 1,2-Epoxyhexane

Chemical Property:

• Appearance/Colour: clear colorless liquid
• Vapor Pressure: 21.1mmHg at 25°C
• Melting Point: 94°C
• Refractive Index: n20/D 1.406
• Boiling Point: 117.1°Cat760mmHg
• Flash Point: 21.8°C
• PSA: 12.53000
• Density: 0.871g/cm³
• LogP: 1.57540
• Storage Temp.: 2-8°C
• Solubility.: Difficult to mix.
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 100.088815002
• Heavy Atom Count: 7
• Complexity: 52.1

Purity/Quality:

98% ^*data from raw suppliers

1,2-Epoxyhexane ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F,Xn
• Statements: 11-22-36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCCCC1CO1
• Uses: 1,2-Epoxyhexane is used as chemical reagent, organic intermediates, fine chemicals, pharmaceutical research and development.

Technology Process of 1,2-Epoxyhexane

There total 125 articles about 1,2-Epoxyhexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

1-hexene (592-41-6,25067-06-5) → 1,2-Epoxyhexane (1436-34-6) + n-hexan-2-ol (626-93-7) + n-hexan-2-one (591-78-6)

Guidance literature:

With iodosylbenzene; (n-Bu₄N)4H(Mn)PW₁₁O₃₉; In acetonitrile; at 24 ℃; for 2h; Product distribution; other reagent, other catalysts, other time;

DOI:10.1021/ja00263a046

Reference yield: 50.0%

1-hexene (592-41-6,25067-06-5) → 1,2-Epoxyhexane (1436-34-6) + rac-2-hydroxyhexanoic acid (636-36-2,6064-63-7) + valeric acid (109-52-4)

Guidance literature:

With [γ-W10SiO36(PhPO)2][TBA]4; dihydrogen peroxide; In acetonitrile; at 90 - 120 ℃; for 0.833333h; microwave irradiation;

DOI:10.1021/ol061197o

Reference yield: 29.0%

1-hexene (592-41-6,25067-06-5) → 1,2-Epoxyhexane (1436-34-6) + 1-hexene-3-ol (4798-44-1,67928-93-2) + 1-hexene-3-one (1629-60-3) + hexanal (66-25-1)

Guidance literature:

With iodosylbenzene; 5,10,15,20-tetraphenyl-21 H,23-H-porphine manganese(III)chloride; In benzene; for 2h; Ambient temperature; anaerobic cond.;

DOI:10.1016/S0040-4020(01)98805-2

upstream raw materials:

1-hexene

6-iodo-1,2-epoxyhexane

1,2-epoxy-2-hexyl(triphenyl)silane

methanol

Downstream raw materials:

Hexane-1,2-diol

1-(phenylthio)-2-hexanol

decan-5-ol

formaldehyd

Refernces

• 1、 Salari, Hadi,Robatjazi, Hossein,Hormozi-Nezhad, Mohammad Reza,Padervand, Mohsen,Gholami, Mohammad Reza. "Colloidal gold nanoparticles: An unexpected catalytic activity in aqueous phase with dioxygen". . p. 1219 - 1222. Retrieved 2014.
• 2、 Bhunia, Susmita,Jana, Sreyashi,Saha, Debraj,Dutta, Buddhadeb,Koner, Subratanath. "Catalytic olefin epoxidation over cobalt(ii)-containing mesoporous silica by molecular oxygen in dimethylformamide medium". . p. 1820 - 1828. Retrieved 2014.
• 3、 Abdel Aziz, Ayman A.. "Synthesis, spectroscopic characterization, thermal studies, catalytic epoxidation and biological activity of chromium and molybdenum hexacarbonyl bound to a novel N2O2 Schiff base". . p. 77 - 85. Retrieved 2010.
• 4、 Hammond, Ceri,Straus, Julian,Righettoni, Marco,Pratsinis, Sotiris E.,Hermans, Ive. "Nanoparticulate tungsten oxide for catalytic epoxidations". . p. 321 - 327. Retrieved 2013.
• 5、 Zhang, Weijie,Jiang, Pingping,Wang, Ying,Zhang, Jian,Zhang, Pingbo. "Manganese(III) Tetraphenylporphyrin Encapsulated by Ion-Modified Hexagonal Mesoporous Silica With Unexpected Enhanced Epoxidation Selectivity". . p. 1765 - 1772. Retrieved 2016.
• 6、 Mirzaee, Mahdi,Bahramian, Bahram,Amoli, Adonis. "Schiff base-functionalized boehmite nanoparticle-supported molybdenum and vanadium complexes: Efficient catalysts for the epoxidation of alkenes". . p. 593 - 600. Retrieved 2015.
• 7、 Lv, Hongjin,Song, Jie,Geletii, Yurii V.,Guo, Weiwei,Bacsa, John,Hill, Craig L.. "A hexanuclear cobalt(II) cluster incorporated in a banana-shaped tungstovanadate: [(Co(OH2)Co2VW9O 34)2(VW6O26)]17-". . p. 1720 - 1725. Retrieved 2013.
• 8、 Lv, Zhanao,Choe, Cholho,Wu, Yunfeng,Wang, Haibin,Chen, Zhuqi,Li, Guangxing,Yin, Guochuan. "Non-redox metal ions accelerated oxygen atom transfer by Mn-Me3tacn complex with H2O2 as oxygen resource". . p. 46 - 52. Retrieved 2018.
• 9、 Diaz-Cabanas, Maria-Jose,Villaescusa, Luis A.,Camblor, Miguel A.. "Synthesis and catalytic activity of Ti-ITQ-7: A new oxidation catalyst with a three-dimensional system of large pore channels". . p. 761 - 762. Retrieved 2000.
• 10、 Mohamed, Rania G.,Elantabli, Fatma M.,Helal, Nadia H.,El-Medani, Samir M.. "Molybdenum and Tungsten Carbonyl Complexes with N2 Schiff Base Donors: Syntheses, Spectral, Electrochemical, Thermal, Catalytic Epoxidation, and Biological Activity Studies". . p. 1839 - 1850. Retrieved 2015.