2'-Deoxy-7,8-dihydro-8-oxoadenosine

Base Information

Chemical Name:2'-Deoxy-7,8-dihydro-8-oxoadenosine
CAS No.:62471-63-0
Molecular Formula:C₁₀H₁₃N₅O₄
Molecular Weight:267.244
Hs Code.:
DSSTox Substance ID:DTXSID20904172

Synonyms:2'-deoxy-7,8-dihydro-8-oxoadenosine;8-oxo-2'-deoxyadenosine;8-oxo-7,8-dihydro-2'-deoxyadenosine;8-oxo-dA;8-oxo-dAdo

Suppliers and Price of 2'-Deoxy-7,8-dihydro-8-oxoadenosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
8-Oxo-2’-deoxyadenosine
1mg
$ 55.00

Medical Isotopes, Inc.
8-Oxo-2??-deoxyadenosine
5 mg
$ 190.00

Biosynth Carbosynth
2'-Deoxy-8-oxo-adenosine
5 mg
$ 136.50

Biosynth Carbosynth
2'-Deoxy-8-oxo-adenosine
2 mg
$ 71.00

Biosynth Carbosynth
2'-Deoxy-8-oxo-adenosine
1 mg
$ 46.00

Biosynth Carbosynth
2'-Deoxy-8-oxo-adenosine
25 mg
$ 275.00

Biosynth Carbosynth
2'-Deoxy-8-oxo-adenosine
10 mg
$ 210.00

American Custom Chemicals Corporation
2'-DEOXY-8-OXO-ADENOSINE 95.00%
5MG
$ 496.33

Total 7 raw suppliers

Chemical Property of 2'-Deoxy-7,8-dihydro-8-oxoadenosine

Chemical Property:

PKA:10.37±0.20(Predicted)
PSA：139.54000
Density:1.672±0.06 g/cm3(Predicted)
LogP:-0.66400
XLogP3:-1.5
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:267.09675391
Heavy Atom Count:19
Complexity:370

Purity/Quality:

97% ^*data from raw suppliers

8-Oxo-2’-deoxyadenosine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(OC1N2C3=NC=NC(=C3NC2=O)N)CO)O
Isomeric SMILES:C1[C@@H]([C@H](OC1N2C3=NC=NC(=C3NC2=O)N)CO)O
Uses 8-Oxo-2’-deoxyadenosine is the first example of a native DNA lesion that stabilizes human telomeric G-quadruplex DNA.

Technology Process of 2'-Deoxy-7,8-dihydro-8-oxoadenosine

There total 10 articles about 2'-Deoxy-7,8-dihydro-8-oxoadenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 14985-44-5,90968-89-1
8-bromo-2'-deoxyadenosine

: 60-24-2
2-hydroxyethanethiol

: 876380-66-4
(2R,3S,5R)-5-[6-Amino-8-(2-hydroxy-ethylsulfanyl)-purin-9-yl]-2-hydroxymethyl-tetrahydro-furan-3-ol

: 31077-24-4,62471-63-0
8-oxo-7,8-dihydro-2'-deoxyguanosine

: 6974-78-3
8-bromoadenine

Guidance literature:: With triethylamine; In methanol; for 7h; Heating;
DOI:10.1016/j.tetlet.2005.11.099

Reference yield:

duplex AQ-5'-UUUUAAUUAAUUAAUUAAUAUAUUT-3'*3'-AAAATTAATTAATTAATTATATAAA-5', AQ = 2-anthraquinonecarboxamide-N-(2-ethyl) group: duplex AQ-5'-UUUUAAUUAAUUAAUUAAUAUAUUT-3'*3'-AAAATTAATTAATTAATTATATAAA-5', AQ = 2-anthraquinonecarboxamide-N-(2-ethyl) group

: 31077-24-4,62471-63-0
8-oxo-7,8-dihydro-2'-deoxyguanosine

: 5116-24-5,15425-01-1,143156-50-7
2'-deoxy-5-(hydroxymethyl)uridine

: 38645-24-8
trans-5'-carboxy-5,6-dihydroxy-5,6-dihydro thymidine

: 38709-52-3
(+)-cis-(5S,6R)-5,6-dihydroxy-5,6-dihydrothymidine

: 4494-26-2
5-formyl-2'-deoxyuridine

Guidance literature:: duplex AQ-5'-UUUUAAUUAAUUAAUUAAUAUAUUT-3'*3'-AAAATTAATTAATTAATTATATAAA-5', AQ = 2-anthraquinonecarboxamide-N-(2-ethyl) group; With air; at 30 ℃; for 0.25h; pH=7.0; Irradiation; aq. phosphate buffer;

Time; Mechanism; Reactivity; aq. buffer; Enzymatic reaction;
DOI:10.1039/b717437c

Reference yield:

: 3,4-dihydroxy-1,3,5-⁽¹⁰⁾,6,8-estrapentaen-17-one

: 31077-24-4,62471-63-0
8-oxo-7,8-dihydro-2'-deoxyguanosine

: 88847-89-6
7,8-dihydro-8-oxo-2'-deoxyguanosine

Guidance literature:: With 1,4-dihydronicotinamide adenine dinucleotide; In phosphate buffer; at 37 ℃; for 3h; pH=7.4; Further Variations:; Reagents; Product distribution;
DOI:10.1021/tx980083l