Piperazine, 1-(3-(4-fluorophenoxy)propyl)-4-phenyl-

Base Information

Chemical Name:Piperazine, 1-(3-(4-fluorophenoxy)propyl)-4-phenyl-
CAS No.:84344-34-3
Molecular Formula:C19H23FN2O
Molecular Weight:314.403
Hs Code.:
DSSTox Substance ID:DTXSID30233304
Wikidata:Q83114767
Pharos Ligand ID:66TM4AVR91Q7
ChEMBL ID:CHEMBL1940412

Synonyms:BRN 4530212;Piperazine, 1-(3-(4-fluorophenoxy)propyl)-4-phenyl-;1-(3-(4-Fluorophenoxy)propyl)-4-phenylpiperazine;CHEMBL1940412;84344-34-3;C19H23FN2O;DTXSID30233304;C19-H23-F-N2-O;BDBM50362857;LS-112656

Suppliers and Price of Piperazine, 1-(3-(4-fluorophenoxy)propyl)-4-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Piperazine, 1-(3-(4-fluorophenoxy)propyl)-4-phenyl-

Chemical Property:

Vapor Pressure:1.5E-08mmHg at 25°C
Boiling Point:457.4°C at 760 mmHg
Flash Point:230.4°C
Density:1.125g/cm³
XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:314.17944152
Heavy Atom Count:23
Complexity:319

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CCCOC2=CC=C(C=C2)F)C3=CC=CC=C3

Technology Process of Piperazine, 1-(3-(4-fluorophenoxy)propyl)-4-phenyl-

There total 5 articles about Piperazine, 1-(3-(4-fluorophenoxy)propyl)-4-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.9%

: 92-54-6
4-phenyl-1-piperazine

: 3-(4-fluorophenoxy)propyl methanesulfonate

: 84344-34-3
1-(3-(4-fluorophenoxy)propyl)-4-phenylpiperazine

Guidance literature:: With potassium carbonate; potassium iodide; In 1,2-dimethoxyethane; for 12h; Inert atmosphere; Reflux;
DOI:10.1016/j.bmc.2011.12.019

Reference yield:

: 92-54-6
4-phenyl-1-piperazine

: 84344-34-3
1-(3-(4-fluorophenoxy)propyl)-4-phenylpiperazine

Guidance literature:: Multi-step reaction with 2 steps

1: 55 percent / 25percent KOH / acetone / 8 h

2: NaOH / ethanol; H₂O / Heating

With potassium hydroxide; sodium hydroxide; In ethanol; water; acetone;

Reference yield:

: 371-41-5
4-Fluorophenol

: 84344-34-3
1-(3-(4-fluorophenoxy)propyl)-4-phenylpiperazine

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate; potassium iodide / isopropyl alcohol / 1 h / Inert atmosphere; Reflux

2: triethylamine / dichloromethane / 12 h / 20 °C

3: potassium carbonate; potassium iodide / 1,2-dimethoxyethane / 12 h / Inert atmosphere; Reflux

With potassium carbonate; triethylamine; potassium iodide; In 1,2-dimethoxyethane; dichloromethane; isopropyl alcohol;
DOI:10.1016/j.bmc.2011.12.019