2-(1-Phenylethylidene)hydrazinecarboximidamide

Base Information

• Chemical Name: 2-(1-Phenylethylidene)hydrazinecarboximidamide
• CAS No.: 4362-89-4
• Molecular Formula: C9H12N4
• Molecular Weight: 176.221
• NSC Number: 627227,67022
• ChEMBL ID: CHEMBL1644904
• Mol file: 4362-89-4.mol

Synonyms:2-(1-Phenylethylidene)hydrazinecarboximidamide;2-[(E)-1-phenylethylideneamino]guanidine;CHEMBL1644904;NSC627227;4362-89-4;NSC67022;Acetophenonaminoguanidine;MLS001047470;SCHEMBL12217973;SCHEMBL18725202;MRKZNCISKCWGLP-KPKJPENVSA-;REGID_for_CID_5916478;HMS1666J01;2-(1-phenylethylideneamino)guanidine;BDBM50333198;NSC-67022;STK526310;AKOS005459835;NSC-627227;1-[(E)-1-phenylethylideneamino]guanidine;SMR000427857;(2E)-2-(1-phenylethylidene)hydrazinecarboximidamide;InChI=1/C9H12N4/c1-7(12-13-9(10)11)8-5-3-2-4-6-8/h2-6H,1H3,(H4,10,11,13)/b12-7+

Chemical Property of 2-(1-Phenylethylidene)hydrazinecarboximidamide

Chemical Property:

• XLogP3: 0.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 176.106196400
• Heavy Atom Count: 13
• Complexity: 210

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=NN=C(N)N)C1=CC=CC=C1
• Isomeric SMILES: C/C(=N\N=C(N)N)/C1=CC=CC=C1

Technology Process of 2-(1-Phenylethylidene)hydrazinecarboximidamide

There total 6 articles about 2-(1-Phenylethylidene)hydrazinecarboximidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

1-aminoguanidine hydrochloride (1937-19-5,16139-18-7) + acetophenone (98-86-2) → C9H12N4 (4362-89-4)

Guidance literature:

With sodium hydroxide; In water; at 20 ℃;

DOI:10.1039/d1cc04657h

Reference yield: 22.0%

aminoguanidine bicarbonate (2582-30-1) + acetophenone (98-86-2) → 1-phenyl-ethanone carbamimidoylhydrazone (4362-89-4)

Guidance literature:

With hydrogenchloride; In ethanol; water; for 1h; Heating;

DOI:10.1016/0223-5234(91)90148-G

Reference yield:

1-aminoguanidine hydrochloride (1937-19-5,16139-18-7) + acetophenone (98-86-2) → 1-phenyl-ethanone carbamimidoylhydrazone (4362-89-4)

Guidance literature:

1-aminoguanidine hydrochloride; acetophenone; In ethanol; at 100 ℃; for 0.25h; Microwave irradiation;

With sodium hydrogencarbonate; In ethanol; water; for 0.0833333h;

DOI:10.1016/j.bmcl.2010.01.031

upstream raw materials:

acetophenone

aminoguanidine

aminoguanidine bicarbonate

1-aminoguanidine hydrochloride

Downstream raw materials:

oxazolidine-2,4-dione 2-[(1-phenyl-ethylidene)-hydrazone]

5-methyl-oxazolidine-2,4-dione 2-[(1-phenyl-ethylidene)-hydrazone]

5-ethyl-oxazolidine-2,4-dione 2-[(1-phenyl-ethylidene)-hydrazone]

5,5-dimethyl-oxazolidine-2,4-dione 2-[(1-phenyl-ethylidene)-hydrazone]