2,5-DICHLOROFLUOROBENZENE

Base Information

• Chemical Name: 2,5-DICHLOROFLUOROBENZENE
• CAS No.: 348-59-4
• Molecular Formula: C6H3Cl2F
• Molecular Weight: 164.994
• Hs Code.: 29036990
• Mol file: 348-59-4.mol

Synonyms:1,4-Dichloro-2-fluorobenzene;1-Fluoro-2,5-dichlorobenzene;2,5-Dichloro-1-fluorobenzene;2,5-Dichlorofluorobenzene;NSC 10256;

Chemical Property of 2,5-DICHLOROFLUOROBENZENE

Chemical Property:

• Appearance/Colour: clear colorless liquid
• Melting Point: 4 °C
• Refractive Index: 1.5235-1.5255
• Boiling Point: 170.6 °C at 760 mmHg
• Flash Point: 58.1 °C
• PSA: 0.00000
• Density: 1.403 g/cm³
• LogP: 3.13250
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: Difficult to mix.

Purity/Quality:

97% ^*data from raw suppliers

2,5-Dichlorofluorobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1,4-Dichloro-2-fluorobenzene is used as organic synthesis intermediates

Technology Process of 2,5-DICHLOROFLUOROBENZENE

There total 7 articles about 2,5-DICHLOROFLUOROBENZENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

→ 1,4-dichloro-2-fluorobenzene (348-59-4)

Guidance literature:

With trichloroisocyanuric acid; bromine; In tetrachloromethane; at -10 - 100 ℃; for 18h; Photolysis;

Reference yield: 25.2%

para-dichlorobenzene (106-46-7,84348-21-0) → 1-Chloro-4-fluorobenzene (352-33-0) + 4-chloro-1,2-difluorobenzene (696-02-6) + 1,4-dichloro-2-fluorobenzene (348-59-4) + 3,3,6,6-tetrafluoro-1,4-cyclohexadiene (22060-77-1) + 1,4-dichloro-3,3,6-trifluoro-1,4-cyclohexadiene (74298-18-3)

Guidance literature:

With silver(II) fluoride; In hexane; for 18h; Product distribution; Heating;

DOI:10.1021/jo01306a011

Reference yield:

2,3-dichlorofluorobenzene (36556-50-0) → 3,4-dichlorofluorobenzene (1435-49-0) + 3-chlorofluorobenzene (625-98-9) + 1,4-dichloro-2-fluorobenzene (348-59-4) + 1,3-dichloro-4-fluorobenzene (1435-48-9)

Guidance literature:

In acetonitrile; for 10h; Product distribution; Irradiation;

DOI:10.1246/cl.1987.1589

upstream raw materials:

4-chloro-3-fluoroaniline

para-dichlorobenzene

2,3-dichlorofluorobenzene

2,5-dichloro-4-fluorobenzenesulfonyl chloride

Downstream raw materials:

2,5-dichlorophenol

2,5-dichloroanisole

1,4-dichloro-2-fluoro-5-nitrobenzene

2,5-dichloro-4-fluorobenzoic acid