6,7-Dimethoxy-1,3-benzodioxole-5-carboxylic acid

Base Information

Chemical Name:6,7-Dimethoxy-1,3-benzodioxole-5-carboxylic acid
CAS No.:22027-56-1
Molecular Formula:C10H10 O6
Molecular Weight:226.186
Hs Code.:2932999099
DSSTox Substance ID:DTXSID70574142
Nikkaji Number:J16.786J
Wikidata:Q82463079
Mol file:22027-56-1.mol

Synonyms:22027-56-1;6,7-dimethoxy-1,3-benzodioxole-5-carboxylic acid;6,7-Dimethoxy-2H-1,3-benzodioxole-5-carboxylic acid;6,7-Dimethoxybenzo[d][1,3]dioxole-5-carboxylic acid;Dillapiolsaure;DTXSID70574142;AKOS005604829;CS-0336380

Suppliers and Price of 6,7-Dimethoxy-1,3-benzodioxole-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 6,7-Dimethoxy-1,3-benzodioxole-5-carboxylic acid

Chemical Property:

PSA：74.22000
LogP:1.13070
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:226.04773803
Heavy Atom Count:16
Complexity:268

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C2=C(C=C1C(=O)O)OCO2)OC

Technology Process of 6,7-Dimethoxy-1,3-benzodioxole-5-carboxylic acid

There total 8 articles about 6,7-Dimethoxy-1,3-benzodioxole-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 23731-65-9
2,3-dimethoxy-4,5-methylenedioxybenzaldehyde

: 22027-56-1
dillapionic acid

Guidance literature:: With urea hydrogen peroxide adduct; sodium hydroxide; In methanol; water; for 1.5h; Reflux;
DOI:10.1021/np1004278

Reference yield: 80.0%

: 17672-89-8
4.5-Dimethoxy-6-(1-propenyl)-1,3-benzodioxol

: 23731-65-9
2,3-dimethoxy-4,5-methylenedioxybenzaldehyde

: 22027-56-1
dillapionic acid

: 87687-11-4
dihydroxyisodillapiole

Guidance literature:: With potassium permanganate; magnesium sulfate; In acetone; at 0 ℃;

Reference yield:

: 484-31-1
dillapiole

: 22027-56-1
dillapionic acid

Guidance literature:: Multi-step reaction with 3 steps

1: tetrabutylammomium bromide; potassium hydroxide / 0.67 h / 100 °C

2: pyridine; ozone / methanol; chloroform / -15 - 0 °C

3: urea hydrogen peroxide adduct; sodium hydroxide / methanol; water / 1.5 h / Reflux

With pyridine; tetrabutylammomium bromide; urea hydrogen peroxide adduct; ozone; potassium hydroxide; sodium hydroxide; In methanol; chloroform; water;
DOI:10.1021/np1004278