2,4-bis(acetylamino)benzoic acid

Base Information

• Chemical Name: 2,4-bis(acetylamino)benzoic acid
• CAS No.: 73748-78-4
• Molecular Formula: C11H12N2O4
• Molecular Weight: 236.227
• Mol file: 73748-78-4.mol

Synonyms:

Chemical Property of 2,4-bis(acetylamino)benzoic acid

Chemical Property:

• Vapor Pressure: 2.14E-13mmHg at 25°C
• Boiling Point: 560.4°C at 760 mmHg
• Flash Point: 292.7°C
• Density: 1.404g/cm³

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,4-bis(acetylamino)benzoic acid

There total 3 articles about 2,4-bis(acetylamino)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.4%

2,6-dinitrobenzoic acid (603-12-3) + acetic anhydride (108-24-7) → 2,4-diacetylaminobenzoic acid (73748-78-4)

Guidance literature:

In pyridine; Ambient temperature;

Reference yield:

2,4-diacetylaminotoluene (6282-12-8) → 2,4-diacetylaminobenzoic acid (73748-78-4)

Guidance literature:

With calcium permanganate; water; at 95 ℃;

Reference yield:

4-methylbenzene-1,3-diamine (95-80-7,71111-07-4) → 2,4-diacetylaminobenzoic acid (73748-78-4)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid / acetonitrile / 0.25 h

2: potassium permanganate / water / 1.5 h / 80 °C

With potassium permanganate; acetic acid; In water; acetonitrile;

DOI:10.1002/jhet.1669

upstream raw materials:

2,4-diacetylaminotoluene

2,6-dinitrobenzoic acid

acetic anhydride

4-methylbenzene-1,3-diamine

Downstream raw materials:

C₈H₇N₃OS

4-amino-2-aminobenzoic acid

Refernces

• 1、 Mori, Masa-aki,Inoue, Masami,Nunozawa, Tetsuji,Miyahara, Tatsuro,Kozuka, Hiroshi. "Preparation of Some Acetylated, Reduced and Oxidized Derivatives of 2,4-Diaminotoluene and 2,6-Dinitrotoluene". . p. 4859 - 4861. Retrieved 2007/10/02.