2,4-Diacetylaminotoluene

Base Information

• Chemical Name: 2,4-Diacetylaminotoluene
• CAS No.: 6282-12-8
• Molecular Formula: C11H14 N2 O2
• Molecular Weight: 206.244
• NSC Number: 404379,5961
• UNII: 3H583WOQ4E
• DSSTox Substance ID: DTXSID40211931
• Nikkaji Number: J802.426J
• Wikidata: Q27257201
• Mol file: 6282-12-8.mol

Synonyms:2,4-diacetylaminotoluene

Chemical Property of 2,4-Diacetylaminotoluene

Chemical Property:

• Boiling Point: 440.5oC at 760 mmHg
• Flash Point: 190.2oC
• PSA: 58.20000
• Density: 1.199g/cm3
• LogP: 2.05780
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 206.105527694
• Heavy Atom Count: 15
• Complexity: 253

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=C(C=C1)NC(=O)C)NC(=O)C

Technology Process of 2,4-Diacetylaminotoluene

There total 5 articles about 2,4-Diacetylaminotoluene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-methylbenzene-1,3-diamine (95-80-7,71111-07-4) + acetic anhydride (108-24-7) → 2,4-diacetylaminotoluene (6282-12-8)

Guidance literature:

With Co₃O₄ nanoparticles; at 20 ℃; for 0.166667h; Green chemistry;

DOI:10.1007/s11164-016-2631-7

Reference yield:

acetic anhydride (108-24-7) + 4,4'-dimethyl-2,3'-dinitro-ONN-azoxybenzene (102276-79-9) → 2,4-diacetylaminotoluene (6282-12-8) + 3,4-diacetylaminotoluene (5433-07-8) + 2,3'-diacetylamino-4,4'-dimethyl-ONN-azoxybenzene

Guidance literature:

With hydrogenchloride; acetic acid; tin(ll) chloride; Yield given. Multistep reaction. Yields of byproduct given; 1.) 3 h, 2.) C₆H₆, reflux, 1 h;

Reference yield:

4-methylbenzene-1,3-diamine (95-80-7,71111-07-4) + acetic acid (64-19-7,77671-22-8) → 2,4-diacetylaminotoluene (6282-12-8)

Guidance literature:

upstream raw materials:

acetamide

4-methylbenzene-1,3-diamine

acetic anhydride

acetic acid

Downstream raw materials:

2-amino-1-benzylamine

C₈H₇N₃OS

N,N'-(4-amino-6-methyl-m-phenylene)-bis-acetamide

4-amino-2-aminobenzoic acid