6282-12-8

Basic information

• Product Name: 2,4-Diacetylaminotoluene
• Synonyms: 2,4-Diacetylaminotoluene;N-(3-acetamido-4-methylphenyl)acetamide
• CAS NO: 6282-12-8
• Molecular Formula: C₁₁H₁₄N₂O₂
• Molecular Weight: 206.24
• Mol File: 6282-12-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,4-Diacetylaminotoluene(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Diacetylaminotoluene(6282-12-8)
• EPA Substance Registry System: 2,4-Diacetylaminotoluene(6282-12-8)

Safety Data

• Hazardous Substances Data: 6282-12-8(Hazardous Substances Data)

Usage

General Description

2,4-Diacetylaminotoluene, also known as 2,4-dimethylacetanilide, is a chemical compound that belongs to the class of aromatic amines. 2,4-Diacetylaminotoluene is used primarily in the production of dyes, especially azo dyes, and as an intermediate in the synthesis of various organic compounds. It is also used as a precursor for the production of pharmaceuticals and agricultural chemicals. 2,4-Diacetylaminotoluene is a yellowish solid compound with a faint odor, and it is considered to be moderately toxic if ingested, inhaled, or absorbed through the skin. It is important to handle this chemical with caution and to follow proper safety protocols when working with it.

Upstream product

• 108-24-7 acetic anhydride 
• 102276-79-9 4,4'-dimethyl-2,3'-dinitro-ONN-azoxybenzene 
• 95-80-7 4-methylbenzene-1,3-diamine 
• 60-35-5 acetamide 
• 64-19-7 acetic acid 

Downstream Products

• 56850-44-3 4-methyl-2,6-dinitro-m-phenylenediamine 
• 73748-78-4 2,4-diacetylaminobenzoic acid 
• 25199-25-1 2,4-bis-acetylamino-benzaldehyde 
• 405911-06-0 2,4-diacetylamino-5-chlorotoluene 
• 780719-70-2 5-methyl-1,2,3,4-benzenetetramine 
• 4403-69-4 2-amino-1-benzylamine 
• 1606159-00-5 C₈H₇N₃OS 
• 20828-46-0 N,N'-(4-amino-6-methyl-m-phenylene)-bis-acetamide 
• 611-03-0 4-amino-2-aminobenzoic acid 

Relevant articles and documents

Co3O4 nanoparticles prepared by oxidative precipitation method: an efficient and reusable heterogeneous catalyst for N-formylation of amines

Abstract: N-formylation of different amines was carried out with formic acid in the presence of the Co3O4 nanoparticles as an efficient, stable heterogeneous catalyst to give the corresponding formamides under solvent-free conditions. This method has advantages over the reported methods such as high yields, mild conditions, easy work-up and short reaction times. The catalyst was characterized by different techniques such as XRD, SEM and FT-IR spectroscopy. Graphical Abstract: [Figure not available: see fulltext.]

Functionalization of quinazolin-4-ones part 1: Synthesis of novel 7-substituted-2-thioxo quinazolin-4-ones from 4-substituted-2-aminobenzoic acids and PPh3(SCN)2

4-(Nitro, amino, acetylamino)-2-aminobenzoic acid were allowed to react with PPh3(SCN)2 and gave the crossholding 7-nitro, 7-acetylamino- and 7-amino-2-thioxo quinazolin-4-ones respectively. The nature of the substituent at position 4 of the 2-aminobenzoic acids has significant influence on the outcome of the cyclisation reaction with PPh 3(SCN)2. Similarly, the nature of the substituent at position 7 of the 2-substituted quinazolin-4-ones significantly affected the ease with which alkylation reactions could be performed. The alkylation selectivity of the 7- substiuted-2-thioxo quinazolin-4-ones was found to depend on the nature of the alkyl halide and the nature of the substituent at position 2.