1-((3,4-Dihydro-2H-1-benzopyran-2-yl)methyl)-4-(2-methylphenyl)piperazine

Base Information

Chemical Name:1-((3,4-Dihydro-2H-1-benzopyran-2-yl)methyl)-4-(2-methylphenyl)piperazine
CAS No.:81816-83-3
Molecular Formula:C₂₁H₂₆N₂O
Molecular Weight:322.45
Hs Code.:
DSSTox Substance ID:DTXSID801002245

Synonyms:BRN 4547943;1-((3,4-Dihydro-2H-1-benzopyran-2-yl)methyl)-4-(2-methylphenyl)piperazine;Piperazine, 1-((3,4-dihydro-2H-1-benzopyran-2-yl)methyl)-4-(2-methylphenyl)-;81816-83-3;1-[(3,4-Dihydro-2H-1-benzopyran-2-yl)methyl]-4-(2-methylphenyl)piperazine;SCHEMBL2457820;DTXSID801002245;LS-111546

Suppliers and Price of 1-((3,4-Dihydro-2H-1-benzopyran-2-yl)methyl)-4-(2-methylphenyl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1-((3,4-Dihydro-2H-1-benzopyran-2-yl)methyl)-4-(2-methylphenyl)piperazine

Chemical Property:

Vapor Pressure:5.59E-09mmHg at 25°C
Boiling Point:469.3°C at 760 mmHg
Flash Point:135.2°C
Density:1.111g/cm³
XLogP3:4.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:322.204513457
Heavy Atom Count:24
Complexity:393

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1N2CCN(CC2)CC3CCC4=CC=CC=C4O3

Technology Process of 1-((3,4-Dihydro-2H-1-benzopyran-2-yl)methyl)-4-(2-methylphenyl)piperazine

There total 3 articles about 1-((3,4-Dihydro-2H-1-benzopyran-2-yl)methyl)-4-(2-methylphenyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4940-39-0
acide chromone carboxylique-2

: 81816-83-3
1-Chroman-2-ylmethyl-4-o-tolyl-piperazine

Guidance literature:: Multi-step reaction with 4 steps

1: 75 percent / hydrogene / Pd/C / acetic acid / 70 °C

2: thionyl chloride / CHCl₃ / 3 h / Heating

3: triethylamine / benzene

4: LAH / tetrahydrofuran

With lithium aluminium tetrahydride; thionyl chloride; hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; chloroform; acetic acid; benzene;

Reference yield:

: 77039-78-2
2,3-dihydro-4H-benzopyran-2-carboxylic acid chloride

: 81816-83-3
1-Chroman-2-ylmethyl-4-o-tolyl-piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / benzene

2: LAH / tetrahydrofuran

With lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran; benzene;

Reference yield:

: 51939-71-0
chroman-2-carboxylic acid

: 81816-83-3
1-Chroman-2-ylmethyl-4-o-tolyl-piperazine

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride / CHCl₃ / 3 h / Heating

2: triethylamine / benzene

3: LAH / tetrahydrofuran

With lithium aluminium tetrahydride; thionyl chloride; triethylamine; In tetrahydrofuran; chloroform; benzene;