2,2-Diphenylethanol

Base Information

• Chemical Name: 2,2-Diphenylethanol
• CAS No.: 1883-32-5
• Molecular Formula: C14H14O
• Molecular Weight: 198.265
• Hs Code.: 29062900
• European Community (EC) Number: 217-543-6
• NSC Number: 4574
• UNII: T9P7UVI3QY
• DSSTox Substance ID: DTXSID40172179
• Nikkaji Number: J199.704A
• Wikidata: Q72473168
• Mol file: 1883-32-5.mol

Synonyms:2,2-Diphenylethanol;1883-32-5;beta-Phenylphenethyl alcohol;2,2-diphenylethan-1-ol;Benzeneethanol, .beta.-phenyl-;2,2-diphenyl-1-ethanol;T9P7UVI3QY;NSC 4574;NSC-4574;EINECS 217-543-6;2,2-DIPHENYL ETHANOL;2,2-Diphenyl-ethanol;UNII-T9P7UVI3QY;2,2-diphenylethyl alcohol;Benzeneethanol, beta-phenyl-;2,2-Diphenylethanol, 99%;(2,2-Diphenyl)ethyl alcohol;SCHEMBL193835;NYLOEXLAXYHOHH-UHFFFAOYSA-;DTXSID40172179;ETHANOL, 2,2-DIPHENYL-;NSC4574;.BETA.-PHENYLBENZENEETHANOL;MFCD00004729;AKOS009156878;SB83911;AS-44066;FT-0676589;EN300-1869573;J-506834

Chemical Property of 2,2-Diphenylethanol

Chemical Property:

• Appearance/Colour: white powder
• Vapor Pressure: 8.14E-05mmHg at 25°C
• Melting Point: 53-56 °C(lit.)
• Refractive Index: 1.587
• Boiling Point: 190-192oC12 mm Hg(lit.)
• PKA: 14.62±0.10(Predicted)
• Flash Point: >230 °F
• PSA: 20.23000
• Density: 1.079 g/cm³
• LogP: 2.81080
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 198.104465066
• Heavy Atom Count: 15
• Complexity: 148

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,2-Diphenylethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Other Classes -> Other Aromatic Compounds
• Canonical SMILES: C1=CC=C(C=C1)C(CO)C2=CC=CC=C2

Technology Process of 2,2-Diphenylethanol

There total 78 articles about 2,2-Diphenylethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

1,1-diphenyloxirane (882-59-7) → 2,2-diphenyl ethanol (1883-32-5)

Guidance literature:

With 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane; magnesium bis(trifluoromethane solfonyl)imide; In tetrahydrofuran; at 40 ℃; for 24h; regioselective reaction;

DOI:10.1021/jacs.0c05917

Reference yield: 86.0%

1,1-Diphenylethylene (530-48-3) → 2,2-diphenyl ethanol (1883-32-5)

Guidance literature:

With water; diphenyldisulfane; 9-(2-mesityl)-10-methylacridinium perchlorate; In acetonitrile; at 20 ℃; for 24h; Reagent/catalyst; regioselective reaction; Irradiation; Inert atmosphere;

DOI:10.1021/acscatal.6b03388

Reference yield: 80.0%

benzaldehyde (100-52-7) → 2,2-diphenyl ethanol (1883-32-5) + benzyl alcohol (100-51-6,185532-71-2)

Guidance literature:

With zinc; In water; at 90 - 160 ℃; for 2h; Temperature; Reagent/catalyst; Solvent; Concentration; Microwave irradiation; Green chemistry;

DOI:10.1021/acs.oprd.6b00382

upstream raw materials:

styrene oxide

diethyl ether

1,1-Diphenylethylene

formaldehyd

Downstream raw materials:

(E)-1,2-diphenyl-ethene

1,1-diphenyl-2-chloroethane

1,1'-ethylidenebis-benzene

2,2-diphenylethyl benzoate

Refernces

• 1、 Micovic et al.. "-". . p. 340. Retrieved 1957.
• 2、 Brown,Rao. "". . p. 5694. Retrieved 1956.
• 3、 Huang, Binbin,Guo, Lin,Xia, Wujiong. "A facile and versatile electro-reductive system for hydrodefunctionalization under ambient conditions". supporting information. p. 2095 - 2103. Retrieved 2021/03/26.
• 4、 Kobylarski, Marie,Monsigny, Louis,Thuéry, Pierre,Berthet, Jean-Claude,Cantat, Thibault. "Uranyl(VI) Triflate as Catalyst for the Meerwein-Ponndorf-Verley Reaction". supporting information. p. 16140 - 16148. Retrieved 2021/11/01.