N-(tert-Butoxycarbonyloxy)phthalimide

Base Information

Chemical Name:N-(tert-Butoxycarbonyloxy)phthalimide
CAS No.:15263-20-4
Molecular Formula:C13H13 N O5
Molecular Weight:263.25
Hs Code.:
European Community (EC) Number:239-308-7
UNII:94H4RD93T7
DSSTox Substance ID:DTXSID30165090
Nikkaji Number:J218.391I
Wikidata:Q83034239
Mol file:15263-20-4.mol

Synonyms:15263-20-4;N-(tert-Butoxycarbonyloxy)phthalimide;Carbonic Acid tert-Butyl Phthalimido Ester;tert-Butyl (1,3-dioxoisoindolin-2-yl) carbonate;tert-butyl (1,3-dioxoisoindol-2-yl) carbonate;tert-Butyl N-(1,3-dihydro-1,3-dioxoisoindolyl) carbonate;tert-Butyl Phthalimido Carbonate;94H4RD93T7;EINECS 239-308-7;N-(tert-butyloxycarbonyloxy)phthalimide;2-[(tert-butoxycarbonyl)oxy]-1h-isoindole-1,3(2h)-dione;SCHEMBL597194;UNII-94H4RD93T7;DTXSID30165090;MFCD00005889;N-(t-butoxy-carbonyloxy)-phthalimide;AKOS027320894;SB64078;AS-67563;N-(tert-Butoxycarbonyloxy)phthalimide, 97%;CS-0154665;FT-0637206;N-(TERT-BUTOXYCARBONYLOXY)-PHTHALIMIDE;C93423;Carbonic acid tert-butyl(N-phthalimideyl) ester;tert-butyl 1,3-dioxoisoindolin-2-yl carbonate;J-008940;tert-butyl 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl carbonate;1H-Isoindole-1,3(2H)-dione, 2-(((1,1-dimethylethoxy)carbonyl)oxy)-

Suppliers and Price of N-(tert-Butoxycarbonyloxy)phthalimide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TCI Chemical
N-(tert-Butoxycarbonyloxy)phthalimide
1G
$ 40.00

TCI Chemical
N-(tert-Butoxycarbonyloxy)phthalimide >95.0%(HPLC)
5g
$ 131.00

Sigma-Aldrich
N-(tert-Butoxycarbonyloxy)phthalimide 97%
10g
$ 281.00

Crysdot
tert-Butyl(1,3-dioxoisoindolin-2-yl)carbonate 95+%
25g
$ 407.00

Chemenu
tert-Butyl(1,3-dioxoisoindolin-2-yl)carbonate 95%
25g
$ 384.00

Biosynth Carbosynth
N-(tert-Butoxycarbonyloxy)phthalimide
10 g
$ 221.00

Biosynth Carbosynth
N-(tert-Butoxycarbonyloxy)phthalimide
5 g
$ 130.00

American Custom Chemicals Corporation
CARBONIC ACID TERT-BUTYL PHTHALIMIDO ESTER 95.00%
5G
$ 936.00

Alichem
tert-Butyl(1,3-dioxoisoindolin-2-yl)carbonate
25g
$ 406.89

AK Scientific
Carbonicacidtert-butylphthalimidoester
25g
$ 751.00

Total 36 raw suppliers

Chemical Property of N-(tert-Butoxycarbonyloxy)phthalimide

Chemical Property:

Vapor Pressure:1.84E-05mmHg at 25°C
Melting Point:118 °C (dec.)(lit.)
Boiling Point:363.2°Cat760mmHg
Flash Point:173.4°C
PSA：72.91000
Density:1.34g/cm³
LogP:2.08720
Storage Temp.:Inert atmosphere,Room Temperature
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:263.07937252
Heavy Atom Count:19
Complexity:388

Purity/Quality:

97% ^*data from raw suppliers

N-(tert-Butoxycarbonyloxy)phthalimide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36/37/38
Safety Statements: 26-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)ON1C(=O)C2=CC=CC=C2C1=O
Uses N-(tert-Butoxycarbonyloxy)phthalimide may be used in chemical synthesis studies.

Technology Process of N-(tert-Butoxycarbonyloxy)phthalimide

There total 1 articles about N-(tert-Butoxycarbonyloxy)phthalimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 15263-20-4
N-(t-butoxycarbonyloxy)-phthalimide

Guidance literature:: N-Chlorcarbonyloxyphthalimid, tert-Butanol, in Py. + CH2Cl2, -5grad;

Reference yield: 79.0%

: 15263-20-4
N-(t-butoxycarbonyloxy)-phthalimide

: Troc-Val-Orn-Leu-D-Phe(4-Br)-Pro-Val-Orn-Leu-D-Phe(4-Br)-Pro

: Troc-Val-Orn(Boc)-Leu-D-Phe(4-Br)-Pro-Val-Orn(Boc)-Leu-D-Phe(4-Br)-Pro

Guidance literature:: With TEA; In N,N-dimethyl-formamide; for 1h; Ambient temperature;
DOI:10.1246/bcsj.61.2220

Reference yield:

: 15263-20-4
N-(t-butoxycarbonyloxy)-phthalimide

: (S)-4-[(R)-1-(4-Methanesulfonyl-phenyl)-ethyl]-3-methyl-piperazine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: TMP / acetonitrile / Heating

With thymidine 5'-phosphate; In acetonitrile;
DOI:10.1021/jm0155401