(S)-4-N-Boc-2-methylpiperazine

Base Information Edit

Chemical Name:(S)-4-N-Boc-2-methylpiperazine
CAS No.:147081-29-6
Molecular Formula:C10H20N2O2
Molecular Weight:200.281
Hs Code.:29335990
European Community (EC) Number:628-826-2
DSSTox Substance ID:DTXSID40427474
Wikidata:Q72450031
Mol file:147081-29-6.mol

Synonyms:147081-29-6;(S)-4-N-Boc-2-methylpiperazine;(S)-4-N-Boc-2-methyl piperazine;(S)-4-Boc-2-methylpiperazine;(s)-tert-butyl 3-methylpiperazine-1-carboxylate;(S)-1-Boc-3-methylpiperazine;tert-butyl (3S)-3-methylpiperazine-1-carboxylate;(s)-1-boc-3-methyl-piperazine;tert-Butyl (S)-3-methyl-1-piperazinecarboxylate;tert-butyl (S)-3-methylpiperazine-1-carboxylate;1-Piperazinecarboxylic acid, 3-methyl-, 1,1-dimethylethyl ester, (3S)-;(S)-tert-butyl-3-methylpiperazine-1-carboxylate;(s)-3-methyl-piperazine-1-carboxylic acid tert-butyl ester;MFCD02683204;(s)-4-n-boc-2-methyl-piperazine;SCHEMBL16843;1-BOC-3-(S)-methylpiperazine;(s)-4-boc-2-methyl piperazine;4-boc-2-(s)-methyl-piperazine;2-(S)-methyl-4-Boc-piperazine;DTXSID40427474;FMLPQHJYUZTHQS-QMMMGPOBSA-N;(S)-2-methyl-4-N-BOC-piperazine;AKOS005258552;AC-2196;AC-2197;AM81349;CS-W008923;AS-37117;BP-11327;HY-40040;(s)-1-tert-butoxycarbonyl-3-methylpiperazine;2-(S)-methyl-4-(tertbutoxycabonyl)piperazine;tert-butyl (3S)-3-methylpiperazinecarboxylate;EN300-108382;(3S)-1-tert-butyloxycarbonyl-3-methylpiperazine;(5)-tert-butyl 3-methylpiperazine-1-carboxylate;(S)-4-(tert-butoxycarbonyl)-2-methylpiperazine;tert-butyl(3S)-3-methylpiperazine-1-carboxylate;(35)-tert-butyl-3-methylpiperazine-1-carboxylate;(3S)-tert-butyl 3-methylpiperazine-1-carboxylate;(3S)-tert-butyl-3-methylpiperazine-1-carboxylate;(S)-4-N-(tert-butoxycarbonyl)-2-methylpiperazine;tert-butyl (3S)-3-methyl-1-piperazinecarboxylate;tert-butyl-(3S)-3-methylpiperazine-1-carboxylate;W-205650;1,1-dimethylethyl (3S)-3-methyl-1-piperazinecarboxylate;1,1-dimethylethyl(3s)-3-methyl-1-piperazinecarboxylate;(3S)-3-Methylpiperazine-1-carboxylic acid tert-butyl ester;(S)-3-methylpiperazine-1-carboxylic acid tert-butyl ester;3-(s)-methyl-piperazine-1-carboxylic acid tert-butyl ester;(S)-3-methyl-piperazine-1-carboxylic acid, tert-butyl ester;(3s)-3-methyl-1-piperazinecarboxylic acid, 1,1-dimethylethyl ester;3-Methyl-(3S)-1-piperazinecarboxylic acid, 1,1-dimethylethyl ester

Suppliers and Price of (S)-4-N-Boc-2-methylpiperazine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-4-Boc-2-methylpiperazine
25g
$ 305.00

SynQuest Laboratories
(3S)-3-Methylpiperazine, N1-Boc protected
5 g
$ 28.00

Sigma-Aldrich
(S)-1-Boc-3-methylpiperazine ≥98%
1 g
$ 95.60

Sigma-Aldrich
(S)-1-Boc-3-methylpiperazine ≥98%
1g-f
$ 92.40

Sigma-Aldrich
(S)-1-Boc-3-methylpiperazine ≥98%
5g-f
$ 333.00

Sigma-Aldrich
(S)-1-Boc-3-methylpiperazine ≥98%
5 g
$ 312.00

Medical Isotopes, Inc.
(S)-tert-Butyl3-methylpiperazine-1-carboxylate 95%
100 g
$ 570.00

JR MediChem
(S)-1-BOC-3-Methylpiperazine 99%
25g
$ 48.00

JR MediChem
(S)-1-BOC-3-Methylpiperazine 99%
100g
$ 168.00

J&W Pharmlab
(S)-1-Boc-3-methyl-piperazine 97%
100g
$ 180.00

Total 122 raw suppliers

Chemical Property of (S)-4-N-Boc-2-methylpiperazine Edit

Chemical Property:

Appearance/Colour:colorless to yellow liquid
Vapor Pressure:0.00755mmHg at 25°C
Melting Point:40-45 °C
Refractive Index:1.459
Boiling Point:268.7 °C at 760 mmHg
PKA:8.52±0.40(Predicted)
Flash Point:116.3 °C
PSA：41.57000
Density:0.997 g/cm³
LogP:1.48190
Storage Temp.:Room temperature.
Sensitive.:Air Sensitive
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:200.152477885
Heavy Atom Count:14
Complexity:211

Purity/Quality:

99% ^*data from raw suppliers

(S)-4-Boc-2-methylpiperazine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 37/38-41-34
Safety Statements: 26-39-45-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CN(CCN1)C(=O)OC(C)(C)C
Isomeric SMILES:C[C@H]1CN(CCN1)C(=O)OC(C)(C)C
Uses Laboratory chemicals, Manufacture of substances. (S)-4-Boc-2-methylpiperazine is a reagent used in the synthesis of benzamide peptidomimetic as non-ATP competitive inihbitors. Reactant involved in the synthesis of biologically activy molecules including:CCR5 antagonists with anti-HIV-1 activityOpioid receptor antagonistsHuman growth hormone secretagogue receptor antagonists for treatment of obesityFatty acid oxidation inhibitors

Technology Process of (S)-4-N-Boc-2-methylpiperazine

There total 8 articles about (S)-4-N-Boc-2-methylpiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%