Hydantoin, 5,5-diphenyl-3-((4-phenylpiperazinyl)methyl)-

Base Information

• Chemical Name: Hydantoin, 5,5-diphenyl-3-((4-phenylpiperazinyl)methyl)-
• CAS No.: 21598-65-2
• Molecular Formula: C26H26N4O2
• Molecular Weight: 426.5102
• DSSTox Substance ID: DTXSID80175962
• Nikkaji Number: J49.455K
• Wikidata: Q83046299
• ChEMBL ID: CHEMBL4560649
• Mol file: 21598-65-2.mol

Synonyms:Hydantoin, 5,5-diphenyl-3-((4-phenylpiperazinyl)methyl)-;21598-65-2;5,5-diphenyl-3-[(4-phenylpiperazin-1-yl)methyl]imidazolidine-2,4-dione;BRN 0724397;5,5-Diphenyl-3-((4-phenylpiperazinyl)methyl)hydantoin;CHEMBL4560649;DTXSID80175962;AKOS034336818;Z44099122

Chemical Property of Hydantoin, 5,5-diphenyl-3-((4-phenylpiperazinyl)methyl)-

Chemical Property:

• Density: 1.247g/cm³
• XLogP3: 4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 426.20557608
• Heavy Atom Count: 32
• Complexity: 639

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CN(CCN1CN2C(=O)C(NC2=O)(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC=CC=C5

Technology Process of Hydantoin, 5,5-diphenyl-3-((4-phenylpiperazinyl)methyl)-

There total 1 articles about Hydantoin, 5,5-diphenyl-3-((4-phenylpiperazinyl)methyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 4-phenyl-1-piperazine (92-54-6) + phenythoin (57-41-0) → 5,5-diphenyl-3-((4-phenylpiperazin-1-yl)methyl)imidazolidine-2,4-dione (21598-65-2)

Guidance literature:

In ethanol; Reflux;

DOI:10.1016/j.bmcl.2019.06.001

upstream raw materials:

formaldehyd

4-phenyl-1-piperazine

phenythoin