2,5-Diacetoxy-2,5-dihydrofuran

Base Information

• Chemical Name: 2,5-Diacetoxy-2,5-dihydrofuran
• CAS No.: 7093-88-1
• Molecular Formula: C8H10O5
• Molecular Weight: 186.164
• NSC Number: 139998
• DSSTox Substance ID: DTXSID00300916
• Nikkaji Number: J2.400.014A
• Mol file: 7093-88-1.mol

Synonyms:7093-88-1;2,5-diacetoxy-2,5-dihydrofuran;2,5-dihydrofuran-2,5-diyl diacetate;(5-acetyloxy-2,5-dihydrofuran-2-yl) acetate;5-(ACETYLOXY)-2,5-DIHYDROFURAN-2-YL ACETATE;NSC139998;SCHEMBL60544;DTXSID00300916;FFLHFURRPPIZTQ-UHFFFAOYSA-N;AKOS030239752;NSC-139998

Chemical Property of 2,5-Diacetoxy-2,5-dihydrofuran

Chemical Property:

• Vapor Pressure: 0.0374mmHg at 25°C
• Boiling Point: 240.7°C at 760 mmHg
• Flash Point: 99.8°C
• Density: 1.24g/cm³
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 186.05282342
• Heavy Atom Count: 13
• Complexity: 221

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)OC1C=CC(O1)OC(=O)C

Technology Process of 2,5-Diacetoxy-2,5-dihydrofuran

There total 8 articles about 2,5-Diacetoxy-2,5-dihydrofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

furan (110-00-9) + [bis(acetoxy)iodo]benzene (3240-34-4) → 2,5-dihydro-2,5-diacetoxyfuran (7093-88-1)

Guidance literature:

With trimethylsulphonium iodide; acetic acid; at 25 ℃; Inert atmosphere;

DOI:10.1039/c6ob01179a

Reference yield: 57.0%

furan (110-00-9) + acetic acid (64-19-7,77671-22-8) → 2,5-dihydro-2,5-diacetoxyfuran (7093-88-1)

Guidance literature:

With sodium acetate; In acetonitrile; at 3 - 7 ℃; anodic oxidation, platinum anode, carbon rod cathod, 2.45 F/mol;

DOI:10.1016/S0040-4039(01)81881-5

Reference yield:

furan (110-00-9) + lead(IV) tetraacetate (546-67-8) + acetic anhydride (108-24-7) → 2,5-dihydro-2,5-diacetoxyfuran (7093-88-1)

Guidance literature:

In diethyl ether; acetic acid;

upstream raw materials:

furan

acetic acid

lead(IV) tetraacetate

acetic anhydride

Downstream raw materials:

1,2-diazine

Acetic acid (3R,3aS,4R,6S,6aR)-6-acetoxy-3-benzoyl-2-phenyl-hexahydro-furo[3,4-d]isoxazol-4-yl ester

Acetic acid (3S,3aS,4R,6S,6aR)-6-acetoxy-3-benzoyl-2-phenyl-hexahydro-furo[3,4-d]isoxazol-4-yl ester

meta-hydroxybenzaldehyde

Refernces

• 1、 Rao, Dodla S.,Reddy, Thurpu R.,Babachary, Kalvacherla,Kashyap, Sudhir. "Regioselective vicinal functionalization of unactivated alkenes with sulfonium iodate(i) reagents under metal-free conditions". . p. 7529 - 7543. Retrieved 2016/08/16.
• 2、 -. "2,5-diacyloxy-2,5-dihydrofuran activators for inorganic per compounds". . . Retrieved 2008/06/13.