Benzophenone, 4-ethoxy-4'-methoxy-

Base Information

• Chemical Name: Benzophenone, 4-ethoxy-4'-methoxy-
• CAS No.: 52886-92-7
• Molecular Formula: C₁₆H₁₆O₃
• Molecular Weight: 256.301
• Hs Code.: 2914509090
• DSSTox Substance ID: DTXSID20200929
• Wikidata: Q83074115
• Mol file: 52886-92-7.mol

Synonyms:52886-92-7;BENZOPHENONE, 4-ETHOXY-4'-METHOXY-;BRN 2375913;4-Ethoxy-4'-methoxybenzophenone;(4-ethoxyphenyl)(4-methoxyphenyl)methanone;Methanone, (4-ethoxyphenyl)(4-methoxyphenyl)-;(4-Ethoxy-phenyl)-(4-methoxy-phenyl)-methanone;4-08-00-02454 (Beilstein Handbook Reference);(4-ethoxyphenyl)-(4-methoxyphenyl)methanone;SCHEMBL11576081;DTXSID20200929;MFCD01662327;LS-38923

Chemical Property of Benzophenone, 4-ethoxy-4'-methoxy-

Chemical Property:

• Vapor Pressure: 1.02E-06mmHg at 25°C
• Melting Point: 112–113°C
• Boiling Point: 403.4°C at 760 mmHg
• Flash Point: 189.4°C
• PSA: 35.53000
• Density: 1.104g/cm³
• LogP: 3.32490
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 256.109944368
• Heavy Atom Count: 19
• Complexity: 274

Purity/Quality:

99% ^*data from raw suppliers

(4-Ethoxy-phenyl)-(4-methoxy-phenyl)-methanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)OC

Technology Process of Benzophenone, 4-ethoxy-4'-methoxy-

There total 4 articles about Benzophenone, 4-ethoxy-4'-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 17.0%

4-fluoro-4'-methoxybenzophenone (345-89-1) + O,O-diethyl benzylphosphonate (1080-32-6) → 4-methoxy-4'-ethoxybenzophenone (52886-92-7)

Guidance literature:

With sodium hydride; In tetrahydrofuran; for 4h; Heating;

DOI:10.1016/0039-128X(86)90042-5

Reference yield:

4-methoxy-benzoyl chloride (100-07-2) + Phenetole (103-73-1) → 4-methoxy-4'-ethoxybenzophenone (52886-92-7)

Guidance literature:

With carbon disulfide; aluminium trichloride;

Reference yield:

→ 4-methoxy-4'-ethoxybenzophenone (52886-92-7)

Guidance literature:

With potassium hydroxide; dihydrogen peroxide;

upstream raw materials:

4-methoxy-benzoyl chloride

Phenetole

4-hydroxy-4'-methoxybenzophenone

ethyl iodide

Downstream raw materials:

1-(4-ethoxy-phenyl)-1-(4-methoxy-phenyl)-ethene

4-methoxy-4'-ethoxythiobenzophenone

1-(4-ethoxy-phenyl)-2-bromo-1-(4-methoxy-phenyl)-ethane

4'-ethoxy-4-hydroxy-deoxybenzoin