(4-(Benzyloxy)-3-methoxyphenyl)methanamine hydrochloride

Base Information

Chemical Name:(4-(Benzyloxy)-3-methoxyphenyl)methanamine hydrochloride
CAS No.:100955-81-5
Molecular Formula:C15H17NO2.ClH
Molecular Weight:279.766
Hs Code.:
DSSTox Substance ID:DTXSID10585813
Mol file:100955-81-5.mol

Synonyms:100955-81-5;(4-(benzyloxy)-3-methoxyphenyl)methanamine hydrochloride;Benzenemethanamine, 3-methoxy-4-(phenylmethoxy)-, hydrochloride (1:1);(3-methoxy-4-phenylmethoxyphenyl)methanamine;hydrochloride;[4-(benzyloxy)-3-methoxyphenyl]methanamine hydrochloride;SCHEMBL42327;DTXSID10585813;VTTGLJYCZBMHLV-UHFFFAOYSA-N;AKOS005063146;4-benzyloxy-3-methoxybenzylamine hydrochloride;EN300-30268;4-benzyloxy-3-methoxy benzylamine hydrochloride;G31366;Z89271744;1-[4-(Benzyloxy)-3-methoxyphenyl]methanamine--hydrogen chloride (1/1)

Suppliers and Price of (4-(Benzyloxy)-3-methoxyphenyl)methanamine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of (4-(Benzyloxy)-3-methoxyphenyl)methanamine hydrochloride

Chemical Property:

Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:279.1026065
Heavy Atom Count:19
Complexity:229

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)CN)OCC2=CC=CC=C2.Cl

Technology Process of (4-(Benzyloxy)-3-methoxyphenyl)methanamine hydrochloride

There total 4 articles about (4-(Benzyloxy)-3-methoxyphenyl)methanamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2426-87-1
3-methoxy-4-(phenylmethoxy)benzaldehyde

: 100955-81-5
(4-(benzyloxy)-3-methoxyphenyl)methanamine hydrochloride

Guidance literature:: 3-methoxy-4-(phenylmethoxy)benzaldehyde; With ammonia; hydrogen; In tert-butyl alcohol; at 120 ℃; for 24h; Autoclave; High pressure;

With hydrogenchloride; at 20 ℃;
DOI:10.1002/anie.201812100

Reference yield:

: 100-39-0
benzyl bromide

: 100955-81-5
(4-(benzyloxy)-3-methoxyphenyl)methanamine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / N,N-dimethyl-formamide / 18 h / 0 - 20 °C

2: lithium aluminium tetrahydride; calcium chloride / tetrahydrofuran / 18 h / 0 - 20 °C

3: hydrogenchloride / water; chloroform / 0 °C

With hydrogenchloride; lithium aluminium tetrahydride; potassium carbonate; calcium chloride; In tetrahydrofuran; chloroform; water; N,N-dimethyl-formamide;
DOI:10.1139/cjc-2018-0193

Reference yield:

: 52805-34-2
4-(benzyloxy)-3-methoxybenzonitrile

: 100955-81-5
(4-(benzyloxy)-3-methoxyphenyl)methanamine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride; calcium chloride / tetrahydrofuran / 18 h / 0 - 20 °C

2: hydrogenchloride / water; chloroform / 0 °C

With hydrogenchloride; lithium aluminium tetrahydride; calcium chloride; In tetrahydrofuran; chloroform; water;
DOI:10.1139/cjc-2018-0193