2-(p-Tolyl)phenol

Base Information

• Chemical Name: 2-(p-Tolyl)phenol
• CAS No.: 101043-55-4
• Molecular Formula: C13H12O
• Molecular Weight: 184.238
• Hs Code.: 2907199090
• Mol file: 101043-55-4.mol

Synonyms:2-hydroxy-4'-methylbiphenyl;[1,1'-Biphenyl]-2-ol,4'-methyl;4'-methyl-2-hydroxy-1,1'-biphenyl;2-(4'-methylphenyl)phenol;4'-Methyl-[1,1'-biphenyl]-2-ol;4'-methylbiphenyl-2-ol;

Chemical Property of 2-(p-Tolyl)phenol

Chemical Property:

• PSA: 20.23000
• LogP: 3.36760

Purity/Quality:

97% ^*data from raw suppliers

2-(4-Methylphenyl)phenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(p-Tolyl)phenol

There total 23 articles about 2-(p-Tolyl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-tolyl iodide (624-31-7) + C19H25NO2Si (1232692-89-5) → 2-(4-methylphenyl)phenol (101043-55-4)

Guidance literature:

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; tetrabutyl ammonium fluoride; sodium t-butanolate; In tetrahydrofuran; water; at 60 ℃; for 1h; Inert atmosphere;

DOI:10.1002/adsc.201000975

Reference yield: 100.0%

p-tolyl triflate (29540-83-8) + (2-hydroxyphenyl)boronic acid anhydride (7551-38-4) → 2-(4-methylphenyl)phenol (101043-55-4)

Guidance literature:

With potassium fluoride; tricyclohexylphosphine; palladium diacetate; In water; N,N-dimethyl-formamide; at 20 ℃; for 5h; Further Variations:; Reagents; Solvents; Product distribution;

DOI:10.1246/cl.2006.164

Reference yield: 99.0%

2-methoxy-4'-methylbiphenyl (92495-53-9) → 2-(4-methylphenyl)phenol (101043-55-4)

Guidance literature:

With boron tribromide; In dichloromethane; at 0 - 25 ℃;

DOI:10.1021/jo049343w

upstream raw materials:

2-Iodophenol

4-methylphenylboronic acid

2-hydroxybromobenzene

2-methoxy-4'-methylbiphenyl

Downstream raw materials:

C₂₉H₃₀OSi

3-methyldibenzo[b,d]furan

trifluoro-methanesulfonic acid 4'''-methyl-[1,1';2',1'';2'',1''']quaterphenyl-2-yl ester

4'''-methyl-[1,2';1',1'';2'',1''']quaterphenyl-2-ol