Ethyl 6-(bromomethyl)-2-oxo-4-thien-2-yl-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Base Information

Chemical Name:Ethyl 6-(bromomethyl)-2-oxo-4-thien-2-yl-1,2,3,4-tetrahydropyrimidine-5-carboxylate
CAS No.:15139-62-5
Molecular Formula:C₁₂H₁₃BrN₂O₃S
Molecular Weight:345.217
Hs Code.:2934999090
DSSTox Substance ID:DTXSID00392750
Mol file:15139-62-5.mol

Synonyms:15139-62-5;ethyl 6-(bromomethyl)-2-oxo-4-thien-2-yl-1,2,3,4-tetrahydropyrimidine-5-carboxylate;ethyl 6-(bromomethyl)-2-oxo-4-thiophen-2-yl-3,4-dihydro-1H-pyrimidine-5-carboxylate;Ethyl 6-(bromomethyl)-2-oxo-4-(thiophen-2-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate;DTXSID00392750;IKBCZZXKROFYMW-UHFFFAOYSA-N;AKOS008030063;CS-0288792;EN300-07073;Z56945975;Ethyl6-(bromomethyl)-2-oxo-4-(thiophen-2-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Suppliers and Price of Ethyl 6-(bromomethyl)-2-oxo-4-thien-2-yl-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
ETHYL 6-(BROMOMETHYL)-2-OXO-4-THIEN-2-YL-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE 95.00%
5G
$ 1548.26

American Custom Chemicals Corporation
ETHYL 6-(BROMOMETHYL)-2-OXO-4-THIEN-2-YL-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE 95.00%
2.5G
$ 1227.82

American Custom Chemicals Corporation
ETHYL 6-(BROMOMETHYL)-2-OXO-4-THIEN-2-YL-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE 95.00%
1G
$ 852.55

Total 2 raw suppliers

Chemical Property of Ethyl 6-(bromomethyl)-2-oxo-4-thien-2-yl-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Chemical Property:

Vapor Pressure:9.7E-08mmHg at 25°C
Boiling Point:434.1°Cat760mmHg
Flash Point:216.4°C
PSA：95.67000
Density:1.525g/cm³
LogP:2.97170
XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:343.98303
Heavy Atom Count:19
Complexity:414

Purity/Quality:

97% ^*data from raw suppliers

ETHYL 6-(BROMOMETHYL)-2-OXO-4-THIEN-2-YL-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(NC(=O)NC1C2=CC=CS2)CBr

Technology Process of Ethyl 6-(bromomethyl)-2-oxo-4-thien-2-yl-1,2,3,4-tetrahydropyrimidine-5-carboxylate

There total 4 articles about Ethyl 6-(bromomethyl)-2-oxo-4-thien-2-yl-1,2,3,4-tetrahydropyrimidine-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5948-72-1
ethyl 6-methyl-2-oxo-4-(2-thienyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate

: 15139-62-5
2-Oxo-5-ethoxycarbonyl-6-brommethyl-4--1,2,3,4-tetrahydro-pyrimidin

Guidance literature:: With bromine; In chloroform;
DOI:10.1007/BF00911420

Reference yield:

: 98-03-3
thiophene-2-carbaldehyde

: 15139-62-5
2-Oxo-5-ethoxycarbonyl-6-brommethyl-4--1,2,3,4-tetrahydro-pyrimidin

Guidance literature:: Multi-step reaction with 2 steps

1: aq. HCl / methanol

2: Br₂ / CHCl₃

With hydrogenchloride; bromine; In methanol; chloroform;
DOI:10.1007/BF00911420

Reference yield:

: 141-97-9
ethyl acetoacetate

: 15139-62-5
2-Oxo-5-ethoxycarbonyl-6-brommethyl-4--1,2,3,4-tetrahydro-pyrimidin

Guidance literature:: Multi-step reaction with 2 steps

1: aq. HCl / methanol

2: Br₂ / CHCl₃

With hydrogenchloride; bromine; In methanol; chloroform;
DOI:10.1007/BF00911420