2,3-Dihydroxy-2,3-diphenylbutanedinitrile

Base Information

• Chemical Name: 2,3-Dihydroxy-2,3-diphenylbutanedinitrile
• CAS No.: 10425-22-6
• Molecular Formula: C16H12N2O2
• Molecular Weight: 264.283
• DSSTox Substance ID: DTXSID00506012
• Nikkaji Number: J579.542G
• Mol file: 10425-22-6.mol

Synonyms:2,3-dihydroxy-2,3-diphenylbutanedinitrile;10425-22-6;2,3-dihydroxy-2,3-diphenylsuccinonitrile;DTXSID00506012

Chemical Property of 2,3-Dihydroxy-2,3-diphenylbutanedinitrile

Chemical Property:

• XLogP3: 1.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 264.089877630
• Heavy Atom Count: 20
• Complexity: 392

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C#N)(C(C#N)(C2=CC=CC=C2)O)O

Technology Process of 2,3-Dihydroxy-2,3-diphenylbutanedinitrile

There total 15 articles about 2,3-Dihydroxy-2,3-diphenylbutanedinitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

benzoyl cyanide (613-90-1) → Benzil dicyanohydrin (10425-22-6)

Guidance literature:

With titanium(III) chloride; In acetic acid; for 1h; Ambient temperature;

DOI:10.1021/jo00136a006

Reference yield: 40.0%

pyridine-4-carbaldehyde (872-85-5) + benzoyl cyanide (613-90-1) → 1,2-di(pyridin-4-yl)ethane-1,2-diol (5486-06-6) + Benzil dicyanohydrin (10425-22-6) + 1-(4-pyridyl)-2-cyano-2-phenyl-1,2-ethanediol hydrochloride (81390-25-2)

Guidance literature:

With titanium(III) chloride; In acetic acid; for 2h; Ambient temperature;

DOI:10.1021/jo00136a006

Reference yield: 27.0%

benzoyl cyanide (613-90-1) + acrolein (107-02-8,25068-14-8) → Benzil dicyanohydrin (10425-22-6) + 1-Phenyl-1-cyano-1,2-dihydroxy-3-butene (344308-78-7) + benzoic acid (65-85-0,8013-63-6)

Guidance literature:

With titanium(III) chloride; In tetrahydrofuran; for 1.5h;

DOI:10.1021/jo00158a021

upstream raw materials:

hydrogen cyanide

benzil

potassium cyanide

pyridine-4-carbaldehyde

Downstream raw materials:

benzoic acid ethyl ester

benzaldehyde

1-cyanobenzyl benzoate

2,2-diphenylacetamide