N,N-Dimethyl-9-[(2-nitrophenyl)methyl]-9H-purin-6-amine

Base Information

Chemical Name:N,N-Dimethyl-9-[(2-nitrophenyl)methyl]-9H-purin-6-amine
CAS No.:10549-98-1
Molecular Formula:C14H14N6O2
Molecular Weight:298.304
Hs Code.:
ChEMBL ID:CHEMBL7720
DSSTox Substance ID:DTXSID50554427
Wikidata:Q82435413
Mol file:10549-98-1.mol

Synonyms:10549-98-1;N,N-Dimethyl-9-(2-nitrobenzyl)-9H-purin-6-amine;N,N-Dimethyl-9-[(2-nitrophenyl)methyl]-9H-purin-6-amine;CHEMBL7720;DTXSID50554427

Suppliers and Price of N,N-Dimethyl-9-[(2-nitrophenyl)methyl]-9H-purin-6-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of N,N-Dimethyl-9-[(2-nitrophenyl)methyl]-9H-purin-6-amine

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:298.11782371
Heavy Atom Count:22
Complexity:401

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C1=NC=NC2=C1N=CN2CC3=CC=CC=C3[N+](=O)[O-]

Technology Process of N,N-Dimethyl-9-[(2-nitrophenyl)methyl]-9H-purin-6-amine

There total 1 articles about N,N-Dimethyl-9-[(2-nitrophenyl)methyl]-9H-purin-6-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 15813-53-3
6-chloro-9-(2-nitrobenzyl)-9H-purine

: 124-40-3
dimethyl amine

: 10549-98-1
dimethyl-[9-(2-nitro-benzyl)-9H-purin-6-yl]-amine

Guidance literature:: In ethanol; water; for 15h; Ambient temperature;
DOI:10.1021/jm00398a019

Reference yield: 96.0%

: 10549-98-1
dimethyl-[9-(2-nitro-benzyl)-9H-purin-6-yl]-amine

: 112089-26-6
6-(Dimethylamino)-9-(2-aminobenzyl)-9H-purine

Guidance literature:: With hydrogen; palladium on activated charcoal; In acetic acid; for 1.5h; under 1520 - 2280 Torr;
DOI:10.1016/0223-5234(88)90202-4

Reference yield:

: 10549-98-1
dimethyl-[9-(2-nitro-benzyl)-9H-purin-6-yl]-amine

: 119805-73-1
2-Amino-N-[2-(6-dimethylamino-purin-9-ylmethyl)-phenyl]-acetamide; hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / H₂ / 10percent Pd/C / acetic acid / 1.5 h / 1520 - 2280 Torr

2: 1.) triethylamine, ethyl chloroformate / 1.) THF, 10 min; 2.) THF, acetic acid, r.t., 15 h

3: 85 percent / H₂ / 10percent Pd/C / acetic acid / 1520 - 2280 Torr

With hydrogen; chloroformic acid ethyl ester; triethylamine; palladium on activated charcoal; In acetic acid;
DOI:10.1016/0223-5234(88)90202-4