1-[2-(Thiophen-3-yl)ethyl]pyrimidine-2,4,6(1H,3H,5H)-trione

Base Information

Chemical Name:1-[2-(Thiophen-3-yl)ethyl]pyrimidine-2,4,6(1H,3H,5H)-trione
CAS No.:106860-32-6
Molecular Formula:C10H10N2O3S
Molecular Weight:238.267
Hs Code.:
DSSTox Substance ID:DTXSID80546456
Wikidata:Q82424300
Mol file:106860-32-6.mol

Synonyms:106860-32-6;DTXSID80546456;1-[2-(Thiophen-3-yl)ethyl]pyrimidine-2,4,6(1H,3H,5H)-trione

Suppliers and Price of 1-[2-(Thiophen-3-yl)ethyl]pyrimidine-2,4,6(1H,3H,5H)-trione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-[2-(Thiophen-3-yl)ethyl]pyrimidine-2,4,6(1H,3H,5H)-trione

Chemical Property:

PSA：98.21000
LogP:0.97290
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:238.04121336
Heavy Atom Count:16
Complexity:332

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=O)NC(=O)N(C1=O)CCC2=CSC=C2

Technology Process of 1-[2-(Thiophen-3-yl)ethyl]pyrimidine-2,4,6(1H,3H,5H)-trione

There total 3 articles about 1-[2-(Thiophen-3-yl)ethyl]pyrimidine-2,4,6(1H,3H,5H)-trione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 106860-31-5
N-<2-(3-Thienyl)ethyl>harnstoff

: 105-53-3
diethyl malonate

: 106860-32-6
1-<2-(3-Thienyl)ethyl>pyrimidin-2,4,6(1H,3H,5H)trion

Guidance literature:: With sodium; In ethanol; for 20h; Heating;
DOI:10.1002/hlca.19860690722

Reference yield:

: 59311-67-0
2-(3-thienyl)ethylamine

: 106860-32-6
1-<2-(3-Thienyl)ethyl>pyrimidin-2,4,6(1H,3H,5H)trion

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / conc. aq. HCl, Ac₂O / H₂O / 4 h / 100 °C

2: 80 percent / EtONa / ethanol / 20 h / Heating

With hydrogenchloride; sodium ethanolate; acetic anhydride; In ethanol; water;
DOI:10.3987/R-1986-07-1977

Reference yield:

: 34843-84-0
2-(thiophen-3-yl)ethan-1-amine hydrochloride

: 106860-32-6
1-<2-(3-Thienyl)ethyl>pyrimidin-2,4,6(1H,3H,5H)trion

Guidance literature:: Multi-step reaction with 2 steps

1: H₂O / 2 h / 50 °C / 2 h addition at 50 deg C

2: 90 percent / Na / ethanol / 20 h / Heating

With sodium; In ethanol; water;
DOI:10.1002/hlca.19860690722