1H-Isoindole-1,3(2H)-dione, 2-((3,4-dihydro-3-(4-hydroxyphenyl)-6-iodo-4-oxo-2-quinazolinyl)methyl)-

Base Information

Chemical Name:1H-Isoindole-1,3(2H)-dione, 2-((3,4-dihydro-3-(4-hydroxyphenyl)-6-iodo-4-oxo-2-quinazolinyl)methyl)-
CAS No.:131357-87-4
Molecular Formula:C23H14IN3O4
Molecular Weight:523.2794
Hs Code.:
DSSTox Substance ID:DTXSID90157012
Wikidata:Q83025139

Synonyms:BRN 4769650;1H-Isoindole-1,3(2H)-dione, 2-((3,4-dihydro-3-(4-hydroxyphenyl)-6-iodo-4-oxo-2-quinazolinyl)methyl)-;131357-87-4;C23H14IN3O4;DTXSID90157012;C23-H14-I-N3-O4;LS-84557

Suppliers and Price of 1H-Isoindole-1,3(2H)-dione, 2-((3,4-dihydro-3-(4-hydroxyphenyl)-6-iodo-4-oxo-2-quinazolinyl)methyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1H-Isoindole-1,3(2H)-dione, 2-((3,4-dihydro-3-(4-hydroxyphenyl)-6-iodo-4-oxo-2-quinazolinyl)methyl)-

Chemical Property:

Vapor Pressure:5.38E-21mmHg at 25°C
Boiling Point:712.8°Cat760mmHg
Flash Point:384.9°C
Density:1.78g/cm³
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:523.00290
Heavy Atom Count:31
Complexity:770

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)N(C2=O)CC3=NC4=C(C=C(C=C4)I)C(=O)N3C5=CC=C(C=C5)O

Technology Process of 1H-Isoindole-1,3(2H)-dione, 2-((3,4-dihydro-3-(4-hydroxyphenyl)-6-iodo-4-oxo-2-quinazolinyl)methyl)-

There total 3 articles about 1H-Isoindole-1,3(2H)-dione, 2-((3,4-dihydro-3-(4-hydroxyphenyl)-6-iodo-4-oxo-2-quinazolinyl)methyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 123-30-8
4-amino-phenol

: 134700-31-5
2-(6-Iodo-4-oxo-4H-benzo[d][1,3]oxazin-2-ylmethyl)-isoindole-1,3-dione

: 131357-87-4
2-[3-(4-Hydroxy-phenyl)-6-iodo-4-oxo-3,4-dihydro-quinazolin-2-ylmethyl]-isoindole-1,3-dione

Guidance literature:: With pyridine; Heating;

Reference yield:

: 6780-38-7
N-phthaloylglycine chloride

: 131357-87-4
2-[3-(4-Hydroxy-phenyl)-6-iodo-4-oxo-3,4-dihydro-quinazolin-2-ylmethyl]-isoindole-1,3-dione

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 1) 0 to 5 deg C, 1h, 2) RT, overnight

2: 75 percent / pyridine / Heating

With pyridine;

Reference yield:

: 5326-47-6
2-amino-5-iodobenzoic acid

: 131357-87-4
2-[3-(4-Hydroxy-phenyl)-6-iodo-4-oxo-3,4-dihydro-quinazolin-2-ylmethyl]-isoindole-1,3-dione

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 1) 0 to 5 deg C, 1h, 2) RT, overnight

2: 75 percent / pyridine / Heating

With pyridine;